JAK/STAT signaling regulated intestinal regeneration defends insect pests against pore-forming toxins produced by Bacillus thuringiensis

• Published in: PLoS pathogens Vol. 20; no. 1; p. e1011823
• Main Authors: Wang, Zeyu, Yang, Yanchao, Li, Sirui, Ma, Weihua, Wang, Kui, Soberón, Mario, Yan, Shuo, Shen, Jie, Francis, Frederic, Bravo, Alejandra, Zhang, Jie
• Format: Journal Article Web Resource
• Language: English
• Published: United States Public Library of Science 18.01.2024; Public Library of Science (PLoS)
• Subjects: Agrochemicals; Analysis; Apoptosis; Bacillus thuringiensis; Biological control; Biology and Life Sciences; Biopesticides; Cell cycle; Cell differentiation; Cell proliferation; Chemical pest control; Crop diseases; Crops; Defense mechanisms; Double-stranded RNA; Effectiveness; Entomologie & lutte antiravageur; Entomology & pest control; Epithelium; Gastrointestinal tract; Gene expression; Genes; Health aspects; Insect pests; Insects; Intestine; Intoxication; Kinases; Larvae; Life sciences; Ligands; Medicine and Health Sciences; Nanoparticles; Pest control; Pesticides; Pests; Plant diseases; Pore formation; Prevention; Proteins; Regeneration; Rice; Risk factors; RNA interference; Sciences du vivant; STAT signalling; Stem cells; Sublethal dosage; Toxicity; Toxins; Transcription factors; Tyrosine; China

A variety of coordinated host-cell responses are activated as defense mechanisms against pore-forming toxins (PFTs). Bacillus thuringiensis (Bt) is a worldwide used biopesticide whose efficacy and precise application methods limits its use to replace synthetic pesticides in agricultural settings. He...