Tumor growth suppression using a combination of taxol-based therapy and GSK3 inhibition in non-small cell lung cancer - O’Flaherty, Linda; Shnyder, Steven D.; Cooper, Patricia A.; Cross, Stephen J.; Wakefield, James G.; Pardo, Olivier E.; Seckl, Michael J.; Tavaré, Jeremy M. (PloS one, 2019)
Keywords: Animals; Antineoplastic Agents, Phytogenic - pharmacology; Antineoplastic Agents, Phytogenic - therapeutic use; Biology and Life Sciences; Cancer research; Cancer treatment; Carboplatin; Carcinoma; Carcinoma, Non-Small-Cell Lung - drug therapy; Care and treatment; Cell Line, Tumor; Cell Proliferation - drug effects; Chemotherapy; Chromosome Aberrations - drug effects; Chromosomes; Drug Synergism; Drug Therapy, Combination; Enzymes; Genetic research; Glycogen; Glycogen Synthase Kinase 3 - antagonists & inhibitors; Glycogen Synthase Kinase 3 - genetics; Glycogen Synthase Kinase 3 - metabolism; Glycogen synthesis; Humans; Lung cancer; Lung Neoplasms - drug therapy; Male; Medicine and Health Sciences; Mice; Mice, Nude; Non-small cell lung cancer; Novels; Paclitaxel - pharmacology; Paclitaxel - therapeutic use; Pemetrexed; Polysaccharides; Pyridines - pharmacology; Pyridines - therapeutic use; Pyrimidines - pharmacology; Pyrimidines - therapeutic use; RNA Interference; RNA, Small Interfering - metabolism; Small cell lung cancer; Tumors