Early pathogenesis of the foot-and-mouth disease virus O/JPN/2010 in experimentally infected pigs

• Published in: Journal of Veterinary Medical Science Vol. 80; no. 4; pp. 689 - 700
• Main Authors: KITANO, Rie, SHIMADA, Nobuaki, YAMADA, Manabu, KANNO, Toru, YAMAKAWA, Makoto, YAMAZOE, Reiko, SAKAMOTO, Kenichi, YOSHIDA, Kazuo, MORIOKA, Kazuki, NISHI, Tatsuya, FUKAI, Katsuhiko
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 2018; Japan Science and Technology Agency; The Japanese Society of Veterinary Science
• Subjects: Antigens; Apoptosis; Basal cells; Cell culture; Cell death; DNA nucleotidylexotransferase; Esophagus; Foot & mouth disease; foot-and-mouth disease virus; Heart diseases; histopathology; immunohistochemistry; Inoculation; Myocarditis; Papillae; Pathology; pig; Ribonucleic acid; RNA; RNA viruses; Tissue culture; Tongue; histopathology; foot-and-mouth disease virus; immunohistochemistry; pig

We examined the histological distribution of the lesions and the viral antigen associated with the virus and virus RNA in multisystemic organs in the early stages of foot-and-mouth disease virus (FMDV) O/JPN/2010 infection in pigs. Characteristic lesions commonly observed in pigs with FMD arise foll...