Population-based screening for cancer: hope and hype

• Published in: Nature reviews. Clinical oncology Vol. 13; no. 9; pp. 550 - 565
• Main Authors: Shieh, Yiwey, Eklund, Martin, Sawaya, George F., Black, William C., Kramer, Barnett S., Esserman, Laura J.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.09.2016; Nature Publishing Group
• Subjects: 692/699/67/2195; 692/699/67/2322; 692/699/67/2329; 692/700/1538; 692/700/478/2772; Age Distribution; Cancer screening; Early Detection of Cancer - methods; Early Detection of Cancer - standards; Evaluation; Female; Forecasts and trends; Health Policy; Health Promotion; Humans; Incidence; Male; Mammography - methods; Mass Screening - methods; Medicine & Public Health; Neoplasms - diagnosis; Neoplasms - prevention & control; Oncology; Practice Guidelines as Topic; Precancerous Conditions - prevention & control; Precision medicine; Public health administration; Quality Improvement; review-article; Risk Assessment

Key Points Tumours within any organ site can have a spectrum of biological phenotypes, ranging from indolent to highly aggressive Screening for cancer is most likely to be beneficial when the target tumour type has a relatively uniform biology and a slower rate of progression Not all precursor lesio...