The effects of motor rehabilitation training on clinical symptoms and serum BDNF levels in Parkinson’s disease subjects

• Published in: Canadian journal of physiology and pharmacology Vol. 94; no. 4; pp. 455 - 461
• Main Authors: Angelucci, Francesco, Piermaria, Jacopo, Gelfo, Francesca, Shofany, Jacob, Tramontano, Marco, Fiore, Marco, Caltagirone, Carlo, Peppe, Antonella
• Format: Journal Article
• Language: English
• Published: Canada NRC Research Press 01.04.2016; Canadian Science Publishing NRC Research Press
• Subjects: Activities of Daily Living; Aged; BDNF; Brain; Brain-derived neurotrophic factor; Brain-Derived Neurotrophic Factor - blood; Care and treatment; exercice physique; Female; Gait - physiology; Humans; maladie de Parkinson; Male; Mental health care; Middle Aged; Motor Activity - physiology; motor rehabilitation; Parkinson Disease - blood; Parkinson Disease - physiopathology; Parkinson's disease; Patient outcomes; physical exercise; Physical therapy; Physical Therapy Modalities; Physiological aspects; Rehabilitation; rééducation motrice; Teaching; Therapeutics, Physiological; Up-Regulation - physiology; Canada; exercice physique; BDNF; rééducation motrice; maladie de Parkinson; motor rehabilitation; physical exercise; Parkinson’s disease

Increasing evidence suggests that motor rehabilitation may delay Parkinson’s disease (PD) progression. Moreover, parallel treatments in animals up-regulate brain-derived neurotrophic factor (BDNF). Thus, we investigated the effect of a motor rehabilitation protocol on PD symptoms and BDNF serum leve...