TALEN-mediated targeting of HPV oncogenes ameliorates HPV-related cervical malignancy - Hu, Zheng; Ding, Wencheng; Zhu, Da; Yu, Lan; Jiang, Xiaohui; Wang, Xiaoli; Zhang, Changlin; Wang, Liming; Ji, Teng; Liu, Dan; He, Dan; Xia, Xi; et al. (The Journal of clinical investigation, 2015)
Keywords: Animals; Antineoplastic Agents - therapeutic use; Apoptosis; Biomedical research; Cell Cycle Checkpoints; Cervical cancer; Complications and side effects; Deoxyribonucleases - therapeutic use; DNA Cleavage; DNA, Viral - genetics; Female; Genetic aspects; Health aspects; HEK293 Cells; HeLa Cells; Human papillomavirus; Human papillomavirus 16 - genetics; Humans; Medical research; Mice, Inbred BALB C; Mice, Nude; Mice, Transgenic; Mutation; Oncogene Proteins, Viral - genetics; Papillomavirus E7 Proteins - genetics; Papillomavirus infections; Papillomavirus Infections - therapy; Papillomavirus Infections - virology; Physiological aspects; Plasmids; Repressor Proteins - genetics; Risk factors; Studies; Tumor proteins; Uterine Cervical Neoplasms - therapy; Uterine Cervical Neoplasms - virology; Xenograft Model Antitumor Assays; China