Endothelial ERK signaling controls lymphatic fate specification - Deng, Yong; Atri, Deepak; Eichmann, Anne; Simons, Michael (The Journal of clinical investigation, 2013)
Keywords: Animals; Aorta - pathology; Biomedical research; Body Patterning; Butadienes - pharmacology; Cells, Cultured; Cellular signal transduction; Development and progression; Edema; Endothelium, Lymphatic - embryology; Endothelium, Lymphatic - pathology; Extracellular signal-regulated kinases; Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors; Extracellular Signal-Regulated MAP Kinases - metabolism; Female; Gene Expression; Gene Expression Regulation, Developmental; Genetic aspects; Homeodomain Proteins - genetics; Homeodomain Proteins - metabolism; Human Umbilical Vein Endothelial Cells - metabolism; Human Umbilical Vein Endothelial Cells - physiology; Humans; Kinases; Lymphangiectasis - genetics; Lymphangiectasis - metabolism; Lymphangiectasis - pathology; Lymphangiogenesis; Lymphatic system; Male; MAP Kinase Signaling System; Mice; Mice, Transgenic; Mutation; Mutation, Missense; Nitriles - pharmacology; Noonan syndrome; Phosphorylation; Physiological aspects; Proto-Oncogene Proteins c-akt - metabolism; Proto-Oncogene Proteins c-raf - genetics; Proto-Oncogene Proteins c-raf - metabolism; SOXF Transcription Factors - genetics; SOXF Transcription Factors - metabolism; Transgenic animals; Tumor Suppressor Proteins - genetics; Tumor Suppressor Proteins - metabolism; Up-Regulation; Vascular Endothelial Growth Factor Receptor-3 - metabolism; Veins & arteries