Critical role of DNAX accessory molecule-1 (DNAM-1) in the development of acute graft-versus-host disease in mice - Nabekura, Tsukasa; Shibuya, Kazuko; Takenaka, Eri; Kai, Hirayasu; Shibata, Kai; Yamashita, Yumi; Harada, Kyoichi; Tahara-Hanaoka, Satoko; Honda, Shin-ichiro; Shibuya, Akira; Yokoyama, Wayne M. (Proceedings of the National Academy of Sciences - PNAS, 2010)
Keywords: Acute Disease; Allografts; Animals; Antibodies; Antibodies, Monoclonal - therapeutic use; Antigens; Antigens, Differentiation, T-Lymphocyte - genetics; Antigens, Differentiation, T-Lymphocyte - immunology; Biological Sciences; Blood; Bone marrow; bone marrow transplant; Bone Marrow Transplantation - adverse effects; Bone Marrow Transplantation - immunology; Bone Marrow Transplantation - pathology; CD226 antigen; CD4-Positive T-Lymphocytes - immunology; CD8 antigen; CD8-positive T-lymphocytes; CD8-Positive T-Lymphocytes - immunology; CD8-Positive T-Lymphocytes - pathology; Cell Proliferation; coculture; Female; gamma -Interferon; Graft vs host disease; Graft vs Host Disease - etiology; Graft vs Host Disease - immunology; Graft vs Host Disease - pathology; Graft vs Host Disease - therapy; Graft-versus-host reaction; Immunoglobulins; Immunotherapy; interferon-gamma; Interferon-gamma - biosynthesis; Intestine; intestines; Irradiation; Ligands; Liver; Lymphocytes T; Major histocompatibility complex; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Molecular structure; Mortality; Receptors; Rodents; Splenocytes; T lymphocytes; Transplantation; Transplantation, Homologous; Transplants & implants