Role of Adiponectin in Central Nervous System Disorders

• Published in: Journal of neural transplantation & plasticity Vol. 2018; no. 2018; pp. 1 - 15
• Main Authors: Suppiramaniam, Vishnu, Reed, Miranda N., Moore, Timothy, Amin, Rajesh H., Judd, Robert L., Hong, Hao, Govindarajulu, Manoj, Pinky, Priyanka D., Bloemer, Jenna, Dhanasekaran, Muralikrishnan
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2018; Hindawi; John Wiley & Sons, Inc; Wiley
• Subjects: Adapter proteins; Adipocytes; Antidepressants; Atherosclerosis; Central nervous system; Depression, Mental; Development and progression; Disease; Glucose; Glucose metabolism; Homeostasis; Hypothalamus; Inflammation; Insulin; Ischemia; Kinases; Males; Metabolism; Molecular weight; Musculoskeletal system; Nervous system; Oxidative stress; Phosphorylation; Physiological aspects; Review; Stroke (Disease); Tumor necrosis factor-TNF

Adiponectin, the most abundant plasma adipokine, plays an important role in the regulation of glucose and lipid metabolism. Adiponectin also possesses insulin-sensitizing, anti-inflammatory, angiogenic, and vasodilatory properties which may influence central nervous system (CNS) disorders. Although...