Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment - Bissig, Karl-Dimiter; Wieland, Stefan F.; Tran, Phu; Isogawa, Masanori; Le, Tam T.; Chisari, Francis V.; Verma, Inder M. (The Journal of clinical investigation, 2010)
Keywords: Animal models in research; Animals; Antiviral agents; Biomedical research; Disease Models, Animal; Drug testing; Genetic aspects; Genomes; Health aspects; Hepacivirus; Hepatitis B; Hepatitis B - pathology; Hepatitis B - therapy; Hepatitis B - virology; Hepatitis B virus; Hepatitis C; Hepatitis C - pathology; Hepatitis C - therapy; Hepatitis C - virology; Hepatitis C virus; Hepatitis viruses; Hepatocytes - pathology; Hepatocytes - transplantation; Hepatocytes - virology; Humans; Infections; Liver - pathology; Liver - virology; Liver cancer; Mice; Mice, Knockout; Monkeys & apes; Pathogens; RNA polymerase; Technical Advance; Toxicity; Transplantation Chimera; Transplantation, Heterologous; Viral infections; Viruses; United States