Distinct predictive biomarker candidates for response to anti-CTLA-4 and anti-PD-1 immunotherapy in melanoma patients - Subrahmanyam, Priyanka B.; Dong, Zhiwan; Gusenleitner, Daniel; Giobbie-Hurder, Anita; Severgnini, Mariano; Zhou, Jun; Manos, Michael; Eastman, Lauren M.; Maecker, Holden T.; Hodi, F. Stephen (Journal for immunotherapy of cancer, 2018)
Keywords: Adult; Age; Aged; Analysis; Antibodies; Antineoplastic Agents, Immunological - therapeutic use; Biological markers; Biomarkers; Biomarkers - blood; Cancer; Care and treatment; CD4-Positive T-Lymphocytes - immunology; CD8-Positive T-Lymphocytes - immunology; Chemotherapy; CTLA-4 Antigen - antagonists & inhibitors; Female; Flow cytometry; Gender; Humans; Immune system; Immunology; Immunotherapy; Immunotherapy Biomarkers; Killer Cells, Natural - immunology; Male; Medicine; Medicine & Public Health; Melanoma; Melanoma - blood; Melanoma - drug therapy; Melanoma - immunology; Middle Aged; Oncology; Patient outcomes; Patients; Programmed Cell Death 1 Receptor - antagonists & inhibitors; Research Article; Skin Neoplasms - blood; Skin Neoplasms - drug therapy; Skin Neoplasms - immunology; Treatment Outcome; Tumors; Cytobank; Memory Cell Subsets; Ionomycin Stimulation; Fluidigm; Checkpoint Blockade