The Role of Potassium Channels in Chronic Stress-Induced Brain Injury

• Published in: Biological & pharmaceutical bulletin Vol. 44; no. 2; pp. 169 - 180
• Main Authors: Ren, Jianhui, Guo, Jiquan, Zhu, Shuguang, Wang, Qiyou, Gao, Ruiping, Zhao, Chunhe, Feng, Chuyu, Qin, Cuiying, He, Zhenfeng, Qin, Changyun, Wang, Zhanle, Zang, Linquan
• Format: Journal Article
• Language: English
• Published: Japan The Pharmaceutical Society of Japan 01.02.2021; Pharmaceutical Society of Japan; Japan Science and Technology Agency
• Subjects: Antagonists; Apoptosis; bioinformatics; Brain injury; chronic stress; Drug development; Environmental stress; Genomes; Immersion; Pharmacodynamics; Potassium; potassium channel; Potassium channels; Potassium channels (voltage-gated); retigabine; Ribonucleic acid; RNA; RNA-sequencing (RNA-seq); Therapeutic applications; Traumatic brain injury; Western blotting; potassium channel; brain injury; retigabine; chronic stress; RNA-sequencing (RNA-seq); bioinformatics

Chronic stress-induced brain injury (CSBI) is the organic damage of brain tissue caused by long-term psychological and environmental stress. However, there is no effective drug for the treatment of CSBI. The present study aimed to investigate possible mechanisms of CSBI and to explore related therap...