IFI16 Restricts HSV-1 Replication by Accumulating on the HSV-1 Genome, Repressing HSV-1 Gene Expression, and Directly or Indirectly Modulating Histone Modifications - Johnson, Karen E.; Bottero, Virginie; Flaherty, Stephanie; Dutta, Sujoy; Singh, Vivek Vikram; Chandran, Bala (PLoS pathogens, 2014)
Keywords: Biology and Life Sciences; Bone cancer; Cell Line, Tumor; Colleges & universities; Deoxyribonucleic acid; DNA; Experiments; Gene expression; Gene Expression Regulation, Viral; Genetic aspects; Genome, Viral; Genomes; Health aspects; HEK293 Cells; Herpes simplex virus; Herpes viruses; Herpesvirus 1, Human - physiology; Histones; Histones - genetics; Histones - metabolism; Humans; Infections; Interferon; Microscopy; Nuclear Proteins - genetics; Nuclear Proteins - metabolism; Phosphoproteins - genetics; Phosphoproteins - metabolism; Protein Processing, Post-Translational; Protein research; Proteins; RNA polymerase; Transcription factors; Viral Proteins - biosynthesis; Viral Proteins - genetics; Virus Replication; Virus research