Seminal plasma induces inflammation and enhances HIV-1 replication in human cervical tissue explants - Introini, Andrea; Boström, Stéphanie; Bradley, Frideborg; Gibbs, Anna; Glaessgen, Axel; Tjernlund, Annelie; Broliden, Kristina (PLoS pathogens, 2017)
Keywords: Acquired immune deficiency syndrome; Adult; AIDS; Biology and Life Sciences; CCL20 protein; CCR5 protein; Cervix; Cervix uteri; Cervix Uteri - immunology; Cervix Uteri - virology; Chemokine CCL1 - genetics; Chemokine CCL1 - immunology; Chemokine CCL20 - genetics; Chemokine CCL20 - immunology; Conditioning; Deoxyribonucleic acid; Disease prevention; Disease transmission; DNA; Electrochemical machining; Explants; Exposure; Female; Gene expression; Growth factors; Health aspects; HIV; HIV Infections - immunology; HIV Infections - transmission; HIV Infections - virology; HIV-1 - genetics; HIV-1 - physiology; Human immunodeficiency virus; Humans; Immunoregulation; In Vitro Techniques; Infections; Infectious diseases; Inflammation; Inflammatory response; Interleukin 1; Interleukin 6; Interleukin 7; Interleukin-6 - genetics; Interleukin-6 - immunology; Leukocytes; Leukocytes (neutrophilic); Male; Mathematical analysis; Mathematical models; Medicine; Medicine and Health Sciences; Middle Aged; Monocytes; Mucosa; Neutrophils; Peripheral blood; Plasma; Polymerase chain reaction; Recruitment; Replication; Rodents; Semen; Semen - immunology; Sexual intercourse; Social Sciences; Tumor necrosis factor; Uterus; Virology; Virus Replication; Viruses