Knock-In Reporter Mice Demonstrate that DNA Repair by Non-homologous End Joining Declines with Age - Vaidya, Amita; Mao, Zhiyong; Tian, Xiao; Spencer, Brianna; Seluanov, Andrei; Gorbunova, Vera (PLoS genetics, 2014)
Keywords: Age; Aging; Aging - genetics; Aging - pathology; Animals; Base Sequence; Biology and life sciences; Cancer; Cloning; Deoxyribonucleic acid; DNA; DNA Breaks, Double-Stranded; DNA damage; DNA Damage - genetics; DNA End-Joining Repair - genetics; DNA repair; DNA Repair - genetics; DNA-Binding Proteins - genetics; Efficiency; Fibroblasts; Gene Knock-In Techniques; Gene mutations; Genes, Reporter; Genetic research; Genomes; Green Fluorescent Proteins - genetics; Humans; Mice; Mutation; Proteins; Recombination, Genetic; Research and Analysis Methods; Skin; Software; Studies