A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility - Wei, Meilin; Huang, Fengjie; Zhao, Ling; Zhang, Yunjing; Yang, Wei; Wang, Shouli; Li, Mengci; Han, Xiaolong; Ge, Kun; Qu, Chun; Rajani, Cynthia; Xie, Guoxiang; et al. (EBioMedicine, 2020)
Keywords: Adipose Tissue, Brown - metabolism; Advanced Basic Science; Animals; Bile acids; Body Mass Index; Chenodeoxycholic Acid - metabolism; Cholestenones - metabolism; Clostridiales - metabolism; Clostridiales - pathogenicity; Cohort Studies; Diet, High-Fat - adverse effects; Disease Models, Animal; Disease Susceptibility; Energy expenditure; Gastrointestinal Microbiome; Gene Expression Regulation; GLP-1; Glucagon-Like Peptide 1 - genetics; Glucagon-Like Peptide 1 - metabolism; Gut microbiota; Humans; Ileum - metabolism; Ileum - microbiology; Internal Medicine; Lithocholic Acid - metabolism; Male; Metagenomics - methods; Mice; Mice, Inbred C57BL; Obesity; Obesity - etiology; Obesity - genetics; Obesity - metabolism; Obesity - microbiology; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - genetics; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - metabolism; Research paper; UCP1; Uncoupling Protein 1 - genetics; Uncoupling Protein 1 - metabolism; Ursodeoxycholic Acid - metabolism; Gut microbiota; Energy expenditure; UCP1; Obesity; Bile acids; GLP-1