A tissue level atlas of the healthy human virome

• Published in: BMC biology Vol. 18; no. 1; pp. 55 - 15
• Main Authors: Kumata, Ryuichi, Ito, Jumpei, Takahashi, Kenta, Suzuki, Tadaki, Sato, Kei
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 04.06.2020; BioMed Central; BMC
• Subjects: Analysis; Asthma; Bacterial infections; Biological response modifiers; Blood circulation; Cytomegalovirus; Datasets; Deoxyribonucleic acid; DNA; Epstein-Barr virus; Gene expression; Gene Expression Profiling; Gene sequencing; Genes; Genetic aspects; Genomes; Genotypes; GTEx; Health aspects; Hepatitis; Hepatitis C; Hepatitis C virus; Herpes simplex; Herpes viruses; High-Throughput Nucleotide Sequencing; HIV; Homeostasis; Human body; Human gene expression; Human immunodeficiency virus; Human tissues; Human virome; Humans; Immune response; Immunology; Immunoproliferative diseases; Infection; Infections; Interferon; Leukocytes; Liver; Lymphocytes; Medical research; Microbiome; Microbiomes; Microorganisms; Mutualism; Next-generation sequencing; Organ Specificity; Pipelines; Plasma cells; Ribonucleic acid; RNA; Spleen; Stomach; Studies; Tissues; Transcriptome; Transcriptomics; Viral infections; Virome; Virus diseases; Viruses; Viruses - classification; Viruses - genetics; Viruses - isolation & purification; GTEx; Human virome; Human gene expression; Transcriptome; Microbiome

Human-resident microbes can influence both health and disease. Investigating the microbiome using next-generation sequencing technology has revealed examples of mutualism and conflict between microbes and humans. Comparing to bacteria, the viral component of the microbiome (i.e., the "virome&qu...