Consequences of a high phosphorus intake on mineral metabolism and bone remodeling in dependence of calcium intake in healthy subjects – a randomized placebo-controlled human intervention study

• Published in: Nutrition journal Vol. 15; no. 1; p. 7
• Main Authors: Trautvetter, Ulrike, Jahreis, Gerhard, Kiehntopf, Michael, Glei, Michael
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 19.01.2016; BioMed Central
• Subjects: Adolescent; Adult; adults; Biomarkers - blood; Biomarkers - urine; blood; Bone Density - drug effects; bone metabolism; Bone Remodeling - drug effects; calcium; Calcium carbonate; calcium phosphates; Calcium, Dietary - administration & dosage; Calcium, Dietary - blood; Calcium, Dietary - urine; death; Diet Records; Dietary Supplements; Double-Blind Method; epidemiological studies; excretion; fasting; Female; Fibroblast Growth Factor-23; Fibroblast growth factors; Fibroblast Growth Factors - blood; Health aspects; Healthy Volunteers; Humans; iron absorption; kidney diseases; magnesium; Magnesium - administration & dosage; Magnesium - blood; Magnesium - urine; Male; Middle Aged; mineral metabolism; Nutrition; Phosphates - blood; phosphorus; Phosphorus in the body; Phosphorus, Dietary - administration & dosage; Phosphorus, Dietary - urine; Physiological aspects; placebos; Renal Insufficiency, Chronic; risk; urine; Young Adult; United States

Epidemiological studies reported an association between plasma phosphate concentrations and a higher risk for death and cardiovascular events in subjects free of chronic kidney diseases. The main aims of the present study were to determine the influence of a high phosphorus intake in combination wit...