Morphometric brain organization across the human lifespan reveals increased dispersion linked to cognitive performance

• Published in: PLoS biology Vol. 22; no. 6; p. e3002647
• Main Authors: Li, Jiao, Zhang, Chao, Meng, Yao, Yang, Siqi, Xia, Jie, Chen, Huafu, Liao, Wei
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 20.06.2024; Public Library of Science (PLoS)
• Subjects: Acetylcholine receptors; Adolescent; Adult; Age; Aged; Aged, 80 and over; Aging; Aging - physiology; Biology and Life Sciences; Brain; Brain - diagnostic imaging; Brain - growth & development; Brain - physiology; Brain architecture; Brain research; Child; Child development; Cognition; Cognition - physiology; Cognitive ability; Cognitive tasks; Computer and Information Sciences; Executive Function - physiology; Female; Grants; Health aspects; Human performance; Humans; Life span; Longevity - physiology; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Manifolds; Medical imaging; Medicine and Health Sciences; Middle Aged; Nerve Net - diagnostic imaging; Nerve Net - physiology; Neural networks; Neuroimaging; Neurosciences; Physical Sciences; Position sensing; Research and Analysis Methods; Sensory integration; Similarity; Social Sciences; Young Adult; Young adults; China

The human brain is organized as segregation and integration units and follows complex developmental trajectories throughout life. The cortical manifold provides a new means of studying the brain’s organization in a multidimensional connectivity gradient space. However, how the brain’s morphometric o...