Distinct usage of three C-type lectins by Japanese encephalitis virus: DC-SIGN, DC-SIGNR, and LSECtin

• Published in: Archives of virology Vol. 159; no. 8; pp. 2023 - 2031
• Main Authors: Shimojima, Masayuki, Takenouchi, Atsushi, Shimoda, Hiroshi, Kimura, Naho, Maeda, Ken
• Format: Journal Article
• Language: English
• Published: Vienna Springer-Verlag 01.08.2014; Springer Vienna; Springer Nature B.V
• Subjects: adhesion; Animals; Antibodies; Antigens; Biomedical and Life Sciences; Biomedicine; Cell Adhesion Molecules; Cell Adhesion Molecules - genetics; Cell Adhesion Molecules - metabolism; Cloning; Dengue fever; Dengue virus; Encephalitis; Encephalitis Virus, Japanese; Encephalitis Virus, Japanese - genetics; Encephalitis Virus, Japanese - physiology; Encephalitis, Japanese; Encephalitis, Japanese - genetics; Encephalitis, Japanese - metabolism; Encephalitis, Japanese - virology; endothelial cells; Endothelium; Flavivirus; Genes; genetics; Humans; Infections; Infectious Diseases; Japanese encephalitis virus; Laboratories; Lectins; Lectins, C-Type; Lectins, C-Type - genetics; Lectins, C-Type - metabolism; Liver; Lymphatic system; mannose; Medical Microbiology; metabolism; Mosquitoes; N-acetylglucosamine; Original; Original Article; Pathogens; physiology; Receptors, Cell Surface; Receptors, Cell Surface - genetics; Receptors, Cell Surface - metabolism; Receptors, Virus; Receptors, Virus - genetics; Receptors, Virus - metabolism; Viral infections; Virology; Viruses; West Nile virus; yeasts; Japanese Encephalitis Virus; Japanese Encephalitis; West Nile Virus; Dengue Virus

Infection with West Nile virus and dengue virus, two mosquito-borne flaviviruses, is enhanced by two calcium-dependent lectins: dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN), and its related molecule (DC-SIGNR). The present study examined the relationship b...