Ependymal polarity defects coupled with disorganized ciliary beating drive abnormal cerebrospinal fluid flow and spine curvature in zebrafish - Xie, Haibo; Kang, Yunsi; Liu, Junjun; Huang, Min; Dai, Zhicheng; Shi, Jiale; Wang, Shuo; Li, Lanqin; Li, Yuan; Zheng, Pengfei; Sun, Yi; Han, Qize; et al. (PLoS biology, 2023)
Keywords: Abnormalities; Adolescents; Amino acids; Analysis; Animals; Basal bodies; Biology and Life Sciences; Cerebrospinal fluid; Children; Cilia; Cilia - metabolism; CRISPR; Danio rerio; Defects; Ependyma - metabolism; Ependyma - pathology; Ependymal cells; Fluid flow; Genetic aspects; Genotype & phenotype; Hydrocephalus; Hydrocephalus - genetics; Hydrocephalus - metabolism; Hydrocephalus - pathology; Medicine and Health Sciences; Muscles; Mutants; Mutation; Neuropeptides; Pathogenesis; Physiological aspects; Polarity; Research and Analysis Methods; Scoliosis; Scoliosis - genetics; Scoliosis - metabolism; Scoliosis - pathology; Signaling; Spinal cord; Spinal curvature; Spine; Urotensins - metabolism; Vertebra; Vertebrae; Zebra fish; Zebrafish; United States