Phenotypic characterization of lung macrophages in asthmatic patients: Overexpression of CCL17 - Staples, Karl J.; Hinks, Timothy S.C.; Ward, Jon A.; Gunn, Victoria; Smith, Caroline; Djukanović, Ratko (Journal of allergy and clinical immunology, 2012)
Keywords: 1-Phosphatidylinositol 3-kinase; adrenal cortex hormones; Adrenal Cortex Hormones - administration & dosage; Adult; Allergy and Immunology; Alveoli; Animal models; Asthma; Asthma - drug therapy; Asthma - immunology; Biological and medical sciences; Biomarkers; Biomarkers - metabolism; Bronchus; CCL17 protein; CCL22 protein; CD163 antigen; chemokine; chemokine CCL17; Chemokine CCL17 - genetics; Chemokine CCL17 - metabolism; chemokine CCL22; Chemokines; Chromones - pharmacology; Chronic obstructive pulmonary disease, asthma; Corticoids; Cytokines; disease severity; Drug therapy; enzyme inhibitors; Enzymes; Eosinophilia; Eosinophils - immunology; Female; Flow cytometry; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Gene expression; gene expression regulation; gene overexpression; Genotype & phenotype; Helper cells; Humans; Immune system; Immunopathology; Inflammation; Interleukin 10; Ligands; Lung; Lymphocytes; Lymphocytes T; macrophage; Macrophages; Macrophages - drug effects; Macrophages - immunology; Male; Medical sciences; messenger RNA; Middle Aged; Monocytes; Morpholines - pharmacology; mRNA; patients; Phenotype; phosphatidylinositol 3-kinase; Phosphoinositide-3 Kinase Inhibitors; Pneumology; Proteins; Respiratory tract diseases; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; Sputum; Sputum - drug effects; Sputum - immunology; steroid; Steroid hormones; steroids; Th2 Cells - immunology; Up-Regulation; Young Adult; AF647; chemokine; Arg1; M1; M2; CLEC10A; macrophage; FACS; PE-Cy7; BAL; Asthma; Lin; LDH; MMP; NF-κB; PE-AF610; APC; PI3K; PE; APC-Cy7; MDM