The evolving epidemiology of Clostridium difficile infection in Canadian hospitals during a postepidemic period (2009–2015)

• Published in: Canadian Medical Association journal (CMAJ) Vol. 190; no. 25; pp. E758 - E765
• Main Authors: Katz, Kevin C., MD, Golding, George R., PhD, Du, Tim, MSc, Mulvey, Michael R., PhD, Choi, Kelly Baekyung, MSc, Pelude, Linda, MSc, Alexandre, Stephanie, BA, Gravel, Denise, MSc, Amaratunga, Kanchana R., MD, Taljaard, Monica, PhD, Collet, Jun Chen, MSc, Davis, Ian, MD, Evans, Gerald A., MD, Frenette, Charles, MD, Hota, Susy, MD, Lemieux, Camille, MD, Kibsey, Pamela, MD, Langley, Joanne M., MD, Lee, Bonita E., MD, Longtin, Yves, MD, Mertz, Dominik, MD, Mieusement, Lorraine Maze Dit, MN, Minion, Jessica, MD, Moore, Dorothy L., MD, Richardson, Susan, MD, Science, Michelle, MD, Simor, Andrew E., MD, Stagg, Paula, MN, Suh, Kathryn N., MD, Taylor, Geoffrey, MD, Wong, Alice, MD, Thampi, Nisha, MD
• Format: Journal Article
• Language: English
• Published: Canada Joule Inc 25.06.2018; CMA Impact, Inc
• Subjects: Antibiotics; Canada; Care and treatment; Clinical outcomes; Clostridium infections; Diagnosis; Epidemics; Epidemiology; Evaluation; Health surveillance; Hospitals; Influence; Internal Medicine; Medical care quality; Mortality; Nosocomial infections; Patients; Pediatrics; Public health; Trends; Canada

ABSTRACT Background The clinical and molecular epidemiology of health care–associated Clostridium difficile infection in nonepidemic settings across Canada has evolved since the first report of the virulent North American pulsed-field gel electrophoresis type 1 (NAP1) strain more than 15 years ago....