A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses - Tripathi, Shashank; Balasubramaniam, Vinod R. M. T.; Brown, Julia A.; Mena, Ignacio; Grant, Alesha; Bardina, Susana V.; Maringer, Kevin; Schwarz, Megan C.; Maestre, Ana M.; Sourisseau, Marion; Albrecht, Randy A.; Krammer, Florian; et al. (PLoS pathogens, 2017)
Keywords: Abnormalities; Analysis; Animals; Aquatic insects; Biology and life sciences; Central nervous system; Cytokines; Disease; Disease Models, Animal; Disease susceptibility; Epidemics; Flavivirus; Global health; Gonads; Health aspects; Host-virus relationships; Immune response; Infections; Inflammation; Inflammation - immunology; Inflammation - virology; Inflammatory response; Interferon; Interrogation; Lethality; Life Sciences; Malfunctions; Medicine; Medicine and Health Sciences; Mice; Mice, Inbred C57BL; Mice, Knockout; Microbiology and Parasitology; Neurological diseases; Organs; Outbreaks; Pathogenesis; Pathogens; Phylogeny; Real-Time Polymerase Chain Reaction; Research and Analysis Methods; Signs and symptoms; Stem cells; Vector-borne diseases; Virology; Viruses; West Nile virus; Zika Virus; Zika Virus - genetics; Zika Virus - immunology; Zika Virus - pathogenicity; Zika Virus Infection; Zika Virus Infection - immunology; New York; United States--US