Diminished Macrophage Apoptosis and Reactive Oxygen Species Generation after Phorbol Ester Stimulation in Crohn's Disease - Palmer, Christine D.; Rahman, Farooq Z.; Sewell, Gavin W.; Ahmed, Afshan; Ashcroft, Margaret; Bloom, Stuart L.; Segal, Anthony W.; Smith, Andrew M. (PloS one, 2009)
Keywords: Acetic acid; Activation; Apoptosis; Arthritis; Bacteria; Cell activation; Cell Biology/Cellular Death and Stress Responses; Cell Survival; Crohn Disease - metabolism; Crohn's Disease; Crohns disease; Cytochrome; Cytochrome c; Defects; Dendritic cells; Deoxyribonucleic acid; Depolarization; Diacylglycerol; Diglycerides; Diglycerides - chemistry; DNA; DNA fragmentation; Drug dosages; Endoplasmic reticulum; Endoplasmic Reticulum - metabolism; Gastroenterology; Gastroenterology and Hepatology/Inflammatory Bowel Disease; Gastrointestinal system; Gastrointestinal tract; Gastrointestinal Tract - metabolism; Gastrointestinal Tract - microbiology; Homology; Humans; Immunology/Innate Immunity; Inflammation; Inflammatory bowel diseases; Interleukin 6; Interleukin-6 - metabolism; Kinases; Lymphocytes; Macrophages; Macrophages - metabolism; Medicine; Membrane potential; Membrane Potentials; Mitochondria; Mitochondrial DNA; Neutrophils; Oxygen; p53 Protein; Pathogenesis; Phorbol esters; Phorbol Esters - metabolism; Probiotics; Reactive Oxygen Species; Studies; Tetradecanoylphorbol Acetate - pharmacology; Tumor necrosis factor-TNF; Tumor proteins; Tumor Suppressor Protein p53 - metabolism; United Kingdom--UK