Sublingual immunotherapy for peanut allergy: Long-term follow-up of a randomized multicenter trial

• Published in: Journal of allergy and clinical immunology Vol. 135; no. 5; pp. 1240 - 1248.e3
• Main Authors: Burks, A. Wesley, Wood, Robert A., Jones, Stacie M., Sicherer, Scott H., Fleischer, David M., Scurlock, Amy M., Vickery, Brian P., Liu, Andrew H., Henning, Alice K., Lindblad, Robert, Dawson, Peter, Plaut, Marshall, Sampson, Hugh A.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.05.2015; Elsevier Limited
• Subjects: Adolescent; Allergens - administration & dosage; Allergens - immunology; Allergies; Allergy and Immunology; Arachis - adverse effects; Arachis hypogaea; Basophils - immunology; Basophils - metabolism; Comorbidity; desensitization; Female; follow-up; Follow-Up Studies; Food allergies; food allergy; Humans; Immunoglobulin E - blood; Immunoglobulin E - immunology; Immunotherapy; Male; Peanut allergy; Peanut Hypersensitivity - immunology; Peanut Hypersensitivity - therapy; Peanuts; Plant Proteins, Dietary - administration & dosage; Plant Proteins, Dietary - immunology; Proteins; Sublingual Immunotherapy; Treatment Outcome; follow-up; SLIT; Peanut allergy; SPT; sublingual immunotherapy; OIT; food allergy; OFC; SCIT; desensitization; Oral food challenge; Subcutaneous immunotherapy; Skin prick test; Oral immunotherapy
• ISSN: 0091-6749; 1097-6825; 1097-6825
• DOI: 10.1016/j.jaci.2014.12.1917

We previously reported the initial results of the first multicenter, randomized, double-blind, placebo-controlled clinical trial of peanut sublingual immunotherapy (SLIT), observing a favorable safety profile associated with modest clinical and immunologic effects in the first year. We sought to pro...