Predictive value of bile acids as metabolite biomarkers for gallstone disease: A systematic review and meta-analysis

• Published in: PloS one Vol. 19; no. 7; p. e0305170
• Main Authors: Han, Xu, Wang, Juan, Wu, Yingnan, Gu, Hao, Zhao, Ning, Liao, Xing, Jiang, Miao
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 25.07.2024; Public Library of Science (PLoS)
• Subjects: Bile; Bile acids; Bile Acids and Salts - blood; Bile Acids and Salts - metabolism; Biological markers; Biology and Life Sciences; Biomarkers; Biomarkers - blood; Biomarkers - metabolism; Calculi; California; China; Cholecystectomy; Cholesterol; Chromatography; Comparative analysis; Deoxycholic acid; Diseases; Gallbladder; Gallbladder diseases; Gallstones; Gallstones - blood; Gallstones - metabolism; Homeostasis; Humans; Inclusion; Longitudinal studies; Mass spectrometry; Mass spectroscopy; Medicine and Health Sciences; Meta-analysis; Metabolism; Metabolites; NMR; Nuclear magnetic resonance; Pain; Patients; People and Places; Physical Sciences; Qualitative analysis; Research and Analysis Methods; Scientific imaging; Statistical methods; Systematic review; Taurocholic acid; China; California

The profiles of bile acids (BAs) in patients with gallstone disease (GSD) have been found to be altered markedly though in an inconsistent pattern. This study aims to characterize the variation of the BA profiles in GSD patients, thereby to discover the potential metabolite biomarkers for earlier de...