Performance of different nebulizers in clinical use for Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC)

• Published in: PloS one Vol. 19; no. 5; p. e0300241
• Main Authors: Göhler, Daniel, Oelschlägel, Kathrin, Ouaissi, Mehdi, Giger-Pabst, Urs
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 02.05.2024; Public Library of Science (PLoS)
• Subjects: Aerosols; Antimitotic agents; Antineoplastic agents; Antineoplastic Agents - administration & dosage; Biology and Life Sciences; Cancer; Chemical composition; Chemotherapy; Comparative analysis; Design; Dosage and administration; Droplets; Emission analysis; Engineering and Technology; Equipment Design; Flow rates; Health aspects; Humans; Lasers; Liquid flow; Medicine and Health Sciences; Nebulizers and Vaporizers; Nozzles; Particle Size; Patient outcomes; Physical Sciences; Pressure; Size distribution; Spectral analysis; Spectrometry; Spectrum analysis; Germany
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0300241

Technical ex-vivo comparison of commercial nebulizer nozzles used for Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC). The performance of four different commercial nebulizer nozzles (Nebulizer; HurriChemTM; MCR-4 TOPOL®; QuattroJet) was analysed concerning: i) technical design and principle...