Potential contribution of pineal atrophy and pineal cysts toward vulnerability and clinical characteristics of psychosis

• Published in: NeuroImage clinical Vol. 32; p. 102805
• Main Authors: Takahashi, Tsutomu, Sasabayashi, Daiki, Takayanagi, Yoichiro, Higuchi, Yuko, Mizukami, Yuko, Akasaki, Yukiko, Nishiyama, Shimako, Furuichi, Atsushi, Pham, Tien Viet, Kobayashi, Haruko, Noguchi, Kyo, Suzuki, Michio
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.01.2021; Elsevier
• Subjects: Atrophy - pathology; Clinical high risk; Cysts - pathology; Humans; Magnetic Resonance Imaging; Melatonin; Pineal gland; Pineal Gland - diagnostic imaging; Pineal Gland - pathology; Psychosis; Psychotic Disorders - diagnostic imaging; Psychotic Disorders - etiology; Psychotic Disorders - pathology; Radiology; Regular; Schizophrenia; Schizophrenia - diagnostic imaging; Schizophrenia - pathology; Psychosis; BACS; SCoRS; Melatonin; Magnetic resonance imaging; Pineal gland; Schizophrenia; ARMS; SOFAS; Clinical high risk; JART; PANSS; Social and Occupational Functioning Assessment Scale; Schizophrenia Cognition Rating Scale; Japanese version of the National Adult Reading Test; Positive and Negative Syndrome Scale; At risk mental state; Brief Assessment of Cognition in Schizophrenia

•Pineal morphology was investigated in schizophrenia patients and ARMS subjects.•Pineal volumes were significantly smaller in both groups than in healthy controls.•Pineal cysts were associated with clinical symptomatology in schizophrenia.•Pineal morphology may reflect vulnerability and the clinical...