Incidence of venous thromboembolism and bleeding in patients with malignant central nervous system neoplasm: Systematic review and meta-analysis

• Published in: PloS one Vol. 19; no. 6; p. e0304682
• Main Authors: Veiga, Viviane Cordeiro, Peres, Stela Verzinhasse, Ostolin, Thatiane L. V. D. P., Moraes, Flavia Regina, Belucci, Talita Rantin, Clara, Carlos Afonso, Cavalcanti, Alexandre Biasi, Chaddad-Neto, Feres Eduardo Aparecido, Batistella, Gabriel N. de Rezende, Neville, Iuri Santana, Baeta, Alex M., Yamada, Camilla Akemi Felizardo
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 20.06.2024; Public Library of Science (PLoS)
• Subjects: Aged; Anticoagulants; Bias; Biology and Life Sciences; Bleeding; Central nervous system; Central Nervous System Neoplasms - complications; Central Nervous System Neoplasms - epidemiology; Cohort analysis; Confidence intervals; Disease prevention; Female; Glioma; Gliomas; Health aspects; Hemorrhage - epidemiology; Heterogeneity; Humans; Incidence; Income; Male; Malignancy; Medical Subject Headings-MeSH; Medicine and Health Sciences; Meta-analysis; Morbidity; Mortality; Neoplasia; Neoplasms; Nervous system; Sensitivity analysis; Statistical analysis; Statistical tests; Subgroups; Systematic review; Thromboembolism; Thrombosis; Tumors; Venous Thromboembolism - epidemiology; Venous Thromboembolism - etiology

Central nervous system (CNS) malignant neoplasms may lead to venous thromboembolism (VTE) and bleeding, which result in rehospitalization, morbidity and mortality. We aimed to assess the incidence of VTE and bleeding in this population. Methods: This systematic review and meta-analysis (PROSPERO CRD...