Increased Paternal Age at Conception Is Associated with Transcriptomic Changes Involved in Mitochondrial Function in Elderly Individuals - Nevalainen, Tapio; Kananen, Laura; Marttila, Saara; Jylhävä, Juulia; Jylhä, Marja; Hervonen, Antti; Hurme, Mikko (PloS one, 2016)
Keywords: Age; Aged, 80 and over; Aging - physiology; Autism; Biology and Life Sciences; Chemical energy; Conception (Human reproduction); Deoxyribonucleic acid; DNA; DNA biosynthesis; DNA methylation; DNA repair; Electron transport; Electron Transport - physiology; Female; Gene expression; Gene Expression Profiling; Gene Expression Regulation - physiology; Genetic aspects; Geriatrics; Germ cells; Health aspects; Health risk assessment; Humans; Leukocytes (mononuclear); Male; Male menopause; Medicine and Health Sciences; Mental disorders; Mitochondria; Mitochondria - metabolism; Mitochondrial diseases; Mitochondrial Proteins - biosynthesis; Mutation; Neurodevelopmental disorders; Nonagenarian; Offspring; Older people; Oogonia; Oxidative Phosphorylation; Oxidative stress; Peripheral blood mononuclear cells; Phosphorylation; Population studies; Replication; Research and analysis methods; Schizophrenia; Spermatogonia; Systematic review; Transcriptome - physiology; Translation termination; Finland