HSP105 expression in cutaneous malignant melanoma: Correlation with clinicopathological characteristics

• Published in: PloS one Vol. 16; no. 10; p. e0258053
• Main Authors: Chen, Ke-Jun, Li, Feng-Zeng, Ye, Qian, Jia, Meng, Fang, Sheng
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 07.10.2021; Public Library of Science (PLoS)
• Subjects: Adult; Aged; Analysis; Apoptosis; Biology and Life Sciences; Cancer therapies; Consent; Dermatology; Diagnosis; Female; Gene Expression Regulation, Neoplastic - genetics; Health aspects; Heat shock proteins; Hospitals; HSP110 Heat-Shock Proteins - genetics; Humans; Immune system; Immunohistochemistry; Laboratories; Lesions; Male; Medical prognosis; Medicine and Health Sciences; Melanoma; Melanoma - epidemiology; Melanoma - genetics; Melanoma - pathology; Melanoma, Cutaneous Malignant; Metastases; Metastasis; Middle Aged; Molecular weight; Mutation; Neoplasm Metastasis; Neoplasm Recurrence, Local - epidemiology; Neoplasm Recurrence, Local - genetics; Neoplasm Recurrence, Local - pathology; Patients; Prognosis; Research and Analysis Methods; Skin cancer; Skin Neoplasms - epidemiology; Skin Neoplasms - genetics; Skin Neoplasms - pathology; Staining; Statistical analysis; Thickness; Tumors; Young Adult; China; United Kingdom > UK

Heat shock proteins can protect against stress-associated cellular challenges, but they can also protect some tumors from human immune system monitoring. Heat shock protein 105 (HSP105/110) is a high molecular weight protein whose expression has been reported in many cancers, but few studies on its...