Molecular epidemiology of tuberculosis in Tasmania and genomic characterisation of its first known multi-drug resistant case

• Published in: PloS one Vol. 13; no. 2; p. e0192351
• Main Authors: Gautam, Sanjay S., Mac Aogáin, Micheál, Cooley, Louise A., Haug, Greg, Fyfe, Janet A., Globan, Maria, O’Toole, Ronan F.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 21.02.2018; Public Library of Science (PLoS)
• Subjects: Analysis; Antibiotics; Antigens; Biology and Life Sciences; Clustering; Contact tracing; Deoxyribonucleic acid; DNA; Drug resistance; Epidemiology; Gene sequencing; Genetic aspects; Genomes; Genomic analysis; Genomics; Health surveillance; Hospitals; Infectious diseases; Laboratories; Loci; Lung diseases; Medicine and Health Sciences; Multidrug resistance; Mutation; Mycobacterium; Mycobacterium bovis; Mycobacterium tuberculosis; Phylogeny; Public health; Tuberculosis; Ultrasonic testing; Tasmania; Victoria Australia; Australia; Ireland; Tasmania Australia

The origin and spread of tuberculosis (TB) in Tasmania and the types of strains of Mycobacterium tuberculosis complex (MTBC) present in the population are largely unknown. The aim of this study was to perform the first genomic analysis of MTBC isolates from Tasmania to better understand the epidemio...