Subject Based Registration for Individualized Analysis of Diffusion Tensor MRI

• Published in: PloS one Vol. 10; no. 11; p. e0142288
• Main Authors: Suri, Asif K., Fleysher, Roman, Lipton, Michael L.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 18.11.2015; Public Library of Science (PLoS)
• Subjects: Abnormalities; Accuracy; Adolescent; Adult; Aged; Algorithms; Alzheimer's disease; Alzheimers disease; Brain; Brain - diagnostic imaging; Brain - physiopathology; Brain Injuries - cerebrospinal fluid; Brain Injuries - diagnostic imaging; Brain Injuries - physiopathology; Care and treatment; Central Nervous System - diagnostic imaging; Central Nervous System - physiopathology; Cerebrospinal fluid; Diagnosis; Diffusion; Diffusion Magnetic Resonance Imaging - methods; Diffusion Tensor Imaging; Error analysis; Evaluation; Female; Humans; Magnetic resonance imaging; Male; Medical imaging; Medicine; Methods; Middle Aged; Nervous system diseases; Neuroimaging; Neurosciences; NMR; Nuclear magnetic resonance; Pathology; Patient outcomes; Radiography; Registration; Tomography; Traumatic brain injury; United States

Registration of subject and control brains to a common anatomical space or template is the basis for quantitatively delineating regions of abnormality in an individual brain. Normally, a brain atlas is chosen as the template. Limitations in the registration process result in persistent differences b...