Effects from diet-induced gut microbiota dysbiosis and obesity can be ameliorated by fecal microbiota transplantation: A multiomics approach

• Published in: PloS one Vol. 14; no. 9; p. e0218143
• Main Authors: Guirro, Maria, Costa, Andrea, Gual-Grau, Andreu, Herrero, Pol, Torrell, Helena, Canela, Núria, Arola, Lluis
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 23.09.2019; Public Library of Science (PLoS)
• Subjects: Animals; Anti-Bacterial Agents - pharmacology; Antibiotics; Biochemistry; Biodiversity; Biology and Life Sciences; Biotechnology; Body Weight; Carbohydrates; Care and treatment; Comorbidity; Dehydrogenases; Depletion; Diet; Disease Models, Animal; Disruption; Dysbacteriosis; Dysbiosis; Ecosystems; Environmental changes; Epidemics; Etiology; Etiology (Medicine); Fecal Microbiota Transplantation; Fecal microflora; Feces; Gastrointestinal Microbiome - drug effects; Gut microbiota; High fat diet; Homeostasis; Infrastructure; Intestinal microflora; Male; Medicine and Health Sciences; Metabolism; Metabolites; Metagenome; Metagenomics; Metronidazole; Microbiota; Microbiota (Symbiotic organisms); Neomycin; Obesity; Obesity - physiopathology; Obesity - therapy; Rats; Risk factors; Studies; Surgery; Transplantation; England; United Kingdom > UK; United States > US; Spain

Obesity and its comorbidities are currently considered an epidemic, and the involved pathophysiology is well studied. Hypercaloric diets are tightly related to the obesity etiology and also cause alterations in gut microbiota functionality. Diet and antibiotics are known to play crucial roles in cha...