Associations of lifetime concussion history and repetitive head impact exposure with resting-state functional connectivity in former collegiate American football players: An NCAA 15-year follow-up study

• Published in: PloS one Vol. 17; no. 9; p. e0273918
• Main Authors: Walton, Samuel R, Powell, Jacob R, Brett, Benjamin L, Yin, Weiyan, Kerr, Zachary Yukio, Liu, Mingxia, McCrea, Michael A, Guskiewicz, Kevin M, Giovanello, Kelly S
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 09.09.2022; Public Library of Science (PLoS)
• Subjects: Age; Aged; Aging; Americans; Athletes; Athletic recruitment; Biology and Life Sciences; Brain; Brain Concussion; Brain mapping; Brain research; Cognitive ability; College athletes; College football; Concussion; Degeneration; Dementia; Demographic aspects; Exposure; Follow-Up Studies; Football; Football players; Functional magnetic resonance imaging; Head; Health aspects; Health surveys; Humans; Magnetic resonance imaging; Male; Medicine and Health Sciences; Nervous system; Neural networks; Older people; Participation; Players; Regression analysis; Regression models; Research and Analysis Methods; Social Sciences; Sports injuries; Statistical analysis; Traumatic brain injury; Universities; United States

The objective of this study was to examine associations of lifetime concussion history (CHx) and an advanced metric of lifetime repetitive head impact exposure with resting-state functional connectivity (rsFC) across the whole-brain and among large-scale functional networks (Default Mode; Dorsal Att...