Downregulation of MicroRNA-9 in iPSC-Derived Neurons of FTD/ALS Patients with TDP-43 Mutations - Zhang, Zhijun; Almeida, Sandra; Lu, Yubing; Nishimura, Agnes L.; Peng, Lingtao; Sun, Danqiong; Wu, Bei; Karydas, Anna M.; Tartaglia, Maria C.; Fong, Jamie C.; Miller, Bruce L.; Farese, Robert V.; et al. (PloS one, 2013)
Keywords: Aged; Aging; Amyotrophic lateral sclerosis; Amyotrophic Lateral Sclerosis - genetics; Amyotrophic Lateral Sclerosis - pathology; Analysis; Animal models; Antibiotics; Base Sequence; Biopsy; Brain research; Cardiovascular disease; Cell Differentiation; Cytoplasm; Dementia; Dementia disorders; Deoxyribonucleic acid; DNA; DNA-binding protein; DNA-Binding Proteins - genetics; Down-Regulation; Fibroblasts; Frontotemporal dementia; Frontotemporal Dementia - genetics; Frontotemporal Dementia - pathology; Gene expression; Genetic aspects; Humans; Induced Pluripotent Stem Cells - pathology; Male; Medical schools; Memory; MicroRNA; MicroRNAs; MicroRNAs - genetics; miRNA; Molecular chains; Mutation; Neurodegeneration; Neurogenesis; Neurology; Neurons; Neurons - metabolism; Neurons - pathology; Neurosciences; Pathology; Patients; Phenotype; Pluripotency; Protein binding; Proteins; Ribonucleic acid; RNA; Skin; Staurosporine; Stem cells; Stress; Stresses; San Francisco California; California; United Kingdom--UK; United States--US; Massachusetts