Serum and aqueous humor adiponectin levels correlate with diabetic retinopathy development and progression

• Published in: PloS one Vol. 16; no. 11; p. e0259683
• Main Authors: Yang, Hyun Seung, Choi, Young Je, Han, Hee Yong, Kim, Hak Su, Park, So Hyun, Lee, Kyung Sub, Lim, Sang Hwa, Heo, Doo Jin, Choi, Sangkyung
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 15.11.2021; Public Library of Science (PLoS)
• Subjects: Adiponectin; Adiponectin - blood; Adiponectin - metabolism; Aged; Aged, 80 and over; Angiopoietin; Aqueous Humor - metabolism; Aqueous humour; Biology and Life Sciences; Body mass; Body mass index; Body size; C-reactive protein; C-Reactive Protein - metabolism; Cataracts; Cell adhesion; Correlation; Cytokines; Development and progression; Diabetes; Diabetes mellitus; Diabetic retinopathy; Diabetic Retinopathy - blood; Diabetic Retinopathy - metabolism; Diabetic Retinopathy - pathology; Disease; Evaluation; Eye surgery; Female; Glucose; Growth factors; Health aspects; Health services; Hemoglobin; Humans; Inflammation; Intercellular adhesion molecule 1; Intercellular Adhesion Molecule-1 - blood; Intercellular Adhesion Molecule-1 - metabolism; Interleukin 10; Laboratories; Leptin; Male; Medicine and Health Sciences; Ophthalmology; Patients; Pentraxins; Platelet-derived growth factor; Platelet-Derived Growth Factor - metabolism; Retinopathy; Serum Amyloid P-Component - metabolism; Statistical analysis; Variance analysis; Vascular endothelial growth factor; Vascular Endothelial Growth Factor A - blood; Vascular Endothelial Growth Factor A - metabolism; South Korea; United States > US

To compare adiponectin (APN) levels in the serum and aqueous humor (AH) and evaluate their association with the development/progression of diabetic retinopathy (DR). Diabetic patients with (group 3; n = 59) and without (group 2; n = 39) DR and age- and sex-matched normal subjects (group 1; n = 35) w...