Dynamical system modeling to simulate donor T cell response to whole exome sequencing-derived recipient peptides: Understanding randomness in alloreactivity incidence following stem cell transplantation - Koparde, Vishal; Abdul Razzaq, Badar; Suntum, Tara; Sabo, Roy; Scalora, Allison; Serrano, Myrna; Jameson-Lee, Max; Hall, Charles; Kobulnicky, David; Sheth, Nihar; Feltz, Juliana; Contaifer, Daniel; et al. (PloS one, 2017)
Keywords: Analysis; Antigens; Binding; Biology and Life Sciences; Bone marrow; Cancer; Cell Transplantation; Clinical outcomes; Computer and Information Sciences; Computer simulation; Cytotoxicity; Dynamical systems; Exome sequencing; Genetic aspects; Graft-versus-host reaction; Histocompatibility antigen HLA; Humans; Incidence; Internal medicine; Leukemia; Lymphocytes; Lymphocytes T; Mathematical analysis; Matrix algebra; Matrix methods; Medicine; Medicine and Health Sciences; Minor histocompatibility antigens; Models, Theoretical; Peptides; Peptides - immunology; Pharmacy; Physical Sciences; Physiological aspects; Proteins; Randomness; Research and Analysis Methods; Sequences; Single-nucleotide polymorphism; Stem Cell Transplantation; Stem cells; T cells; T-Lymphocytes - immunology; Transplantation; Transplants & implants; Whole Exome Sequencing; United States; United States--US; Virginia