Choriocapillaris and Choroidal Microvasculature Imaging with Ultrahigh Speed OCT Angiography

• Published in: PloS one Vol. 8; no. 12; p. e81499
• Main Authors: Choi, WooJhon, Mohler, Kathrin J., Potsaid, Benjamin, Lu, Chen D., Liu, Jonathan J., Jayaraman, Vijaysekhar, Cable, Alex E., Duker, Jay S., Huber, Robert, Fujimoto, James G.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 11.12.2013; Public Library of Science (PLoS)
• Subjects: Adult; Angiography; Arterioles; Chemical compounds; Computer engineering; Computer science; Corrosion; Corrosion (Chemistry); Cross-Sectional Studies; Diabetes; Diabetic retinopathy; Drainage; Electrical engineering; Electron micrographs; Electronics; Epithelium; Erythrocytes; Eye; Eye - pathology; Feasibility studies; Fluorescence; Fluorophores; Fovea; Humans; Image acquisition; Image contrast; Laboratories; Macular degeneration; Male; Medical imaging; Microvasculature; Middle Aged; Motion perception; Optical Coherence Tomography; Optical scanners; Optics; Raster scanning; Retina; Retinal pigment epithelium; Studies; Tomography, Optical Coherence - methods; Wavelengths; Young Adult; United States > US; Massachusetts; New Jersey

We demonstrate in vivo choriocapillaris and choroidal microvasculature imaging in normal human subjects using optical coherence tomography (OCT). An ultrahigh speed swept source OCT prototype at 1060 nm wavelengths with a 400 kHz A-scan rate is developed for three-dimensional ultrahigh speed imaging...