Utility of EBUS-TBNA in PET-positive mediastinal lymph nodes in subjects with extra-thoracic malignancy

• Published in: PloS one Vol. 14; no. 3; p. e0213437
• Main Authors: Mehta, Ravindra M., Biraris, Pavankumar, Patil, Shekhar, Singla, Abhinav, Kallur, Kumar, Gasparini, Stefano
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 11.03.2019; Public Library of Science (PLoS)
• Subjects: Benign; Biology and Life Sciences; Bronchoscopy; Cancer; CAT scans; Critical care; Dermatology; Development and progression; Diagnosis; Discordance; Endoscopic Ultrasound-Guided Fine Needle Aspiration - methods; Etiology; Etiology (Medicine); Female; Health aspects; Hospitals; Humans; Liver cancer; Lung cancer; Lymph nodes; Lymph Nodes - diagnostic imaging; Lymphatic Metastasis - diagnostic imaging; Lymphatic system; Lymphocytes; Male; Malignancy; Mediastinal Neoplasms - diagnostic imaging; Mediastinum - diagnostic imaging; Medical diagnosis; Medical research; Medicine; Medicine and Health Sciences; Middle Aged; Neoplasm Staging; Neoplasms - diagnostic imaging; Oncology; Pathology; Patients; Positron emission; Positron emission tomography; Positron Emission Tomography Computed Tomography; Retrospective Studies; Sarcoidosis; Skin; Sleep; Sport utility vehicles; Statistical analysis; Thorax; Tomography; Tuberculosis; Tumors; Ultrasonic imaging; Ultrasound; Ultrasound imaging; Urology; Italy; India

Patients with primary extra-thoracic malignancy (ETM) often have hyper-metabolic mediastinal lymph nodes (HM-MLN) in the PET-scan done for initial staging or post treatment follow-up. There is scant data on the etiology of HM-MLN in such patients, which can also be due to non-malignant causes. We us...