The Relationship of Retinal Vessel Diameters and Fractal Dimensions with Blood Pressure and Cardiovascular Risk Factors
This study aimed to investigate the correlation between quantitative retinal vascular parameters such as central retinal arteriolar equivalent (CRAE) and retinal vascular fractal dimension (D(f)), and cardiovascular risk factors in the Chinese Han population residing in the in islands of southeast C...
Saved in:
| Published in | PloS one Vol. 9; no. 9; p. e106551 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Public Library of Science
04.09.2014
Public Library of Science (PLoS) |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1932-6203 1932-6203 |
| DOI | 10.1371/journal.pone.0106551 |
Cover
Loading…
| Abstract | This study aimed to investigate the correlation between quantitative retinal vascular parameters such as central retinal arteriolar equivalent (CRAE) and retinal vascular fractal dimension (D(f)), and cardiovascular risk factors in the Chinese Han population residing in the in islands of southeast China.
In this cross-sectional study, fundus photographs were collected and semi-automated analysis software was used to analyze retinal vessel diameters and fractal dimensions. Cardiovascular risk factors such as relevant medical history, blood pressure (BP), lipids, and blood glucose data were collected. Subjects had a mean age of 51.9 ± 12.0 years and included 812 (37.4%) males and 1,357 (62.6%) females. Of the subjects, 726 (33.5%) were overweight, 226 (10.4%) were obese, 272 (12.5%) had diabetes, 738 (34.0%) had hypertension, and 1,156 (53.3%) had metabolic syndrome. After controlling for the effects of potential confounders, multivariate analyses found that age (β = 0.06, P = 0.008), sex (β = 1.33, P = 0.015), mean arterial blood pressure (β = -0.12, P<0.001), high-sensitivity C-reactive protein (β = -0.22, P = 0.008), and CRVE (β = 0.23, P<0.001) were significantly associated with CRAE. Age (β = -0.0012, P < 0.001), BP classification (prehypertension: β = -0.0075, P = 0.014; hypertension: β = -0.0131, P = 0.002), and hypertension history (β = -0.0007, P = 0.009) were significantly associated with D(f).
D(f) exhibits a stronger association with BP than CRAE. Thus, D(f) may become a useful indicator of cardiovascular risk. |
|---|---|
| AbstractList | This study aimed to investigate the correlation between quantitative retinal vascular parameters such as central retinal arteriolar equivalent (CRAE) and retinal vascular fractal dimension (D(f)), and cardiovascular risk factors in the Chinese Han population residing in the in islands of southeast China.BACKGROUNDThis study aimed to investigate the correlation between quantitative retinal vascular parameters such as central retinal arteriolar equivalent (CRAE) and retinal vascular fractal dimension (D(f)), and cardiovascular risk factors in the Chinese Han population residing in the in islands of southeast China.In this cross-sectional study, fundus photographs were collected and semi-automated analysis software was used to analyze retinal vessel diameters and fractal dimensions. Cardiovascular risk factors such as relevant medical history, blood pressure (BP), lipids, and blood glucose data were collected. Subjects had a mean age of 51.9 ± 12.0 years and included 812 (37.4%) males and 1,357 (62.6%) females. Of the subjects, 726 (33.5%) were overweight, 226 (10.4%) were obese, 272 (12.5%) had diabetes, 738 (34.0%) had hypertension, and 1,156 (53.3%) had metabolic syndrome. After controlling for the effects of potential confounders, multivariate analyses found that age (β = 0.06, P = 0.008), sex (β = 1.33, P = 0.015), mean arterial blood pressure (β = -0.12, P<0.001), high-sensitivity C-reactive protein (β = -0.22, P = 0.008), and CRVE (β = 0.23, P<0.001) were significantly associated with CRAE. Age (β = -0.0012, P < 0.001), BP classification (prehypertension: β = -0.0075, P = 0.014; hypertension: β = -0.0131, P = 0.002), and hypertension history (β = -0.0007, P = 0.009) were significantly associated with D(f).METHODOLOGY/PRINCIPLE FINDINGSIn this cross-sectional study, fundus photographs were collected and semi-automated analysis software was used to analyze retinal vessel diameters and fractal dimensions. Cardiovascular risk factors such as relevant medical history, blood pressure (BP), lipids, and blood glucose data were collected. Subjects had a mean age of 51.9 ± 12.0 years and included 812 (37.4%) males and 1,357 (62.6%) females. Of the subjects, 726 (33.5%) were overweight, 226 (10.4%) were obese, 272 (12.5%) had diabetes, 738 (34.0%) had hypertension, and 1,156 (53.3%) had metabolic syndrome. After controlling for the effects of potential confounders, multivariate analyses found that age (β = 0.06, P = 0.008), sex (β = 1.33, P = 0.015), mean arterial blood pressure (β = -0.12, P<0.001), high-sensitivity C-reactive protein (β = -0.22, P = 0.008), and CRVE (β = 0.23, P<0.001) were significantly associated with CRAE. Age (β = -0.0012, P < 0.001), BP classification (prehypertension: β = -0.0075, P = 0.014; hypertension: β = -0.0131, P = 0.002), and hypertension history (β = -0.0007, P = 0.009) were significantly associated with D(f).D(f) exhibits a stronger association with BP than CRAE. Thus, D(f) may become a useful indicator of cardiovascular risk.CONCLUSIONS/SIGNIFICANCED(f) exhibits a stronger association with BP than CRAE. Thus, D(f) may become a useful indicator of cardiovascular risk. This study aimed to investigate the correlation between quantitative retinal vascular parameters such as central retinal arteriolar equivalent (CRAE) and retinal vascular fractal dimension (D(f)), and cardiovascular risk factors in the Chinese Han population residing in the in islands of southeast China. In this cross-sectional study, fundus photographs were collected and semi-automated analysis software was used to analyze retinal vessel diameters and fractal dimensions. Cardiovascular risk factors such as relevant medical history, blood pressure (BP), lipids, and blood glucose data were collected. Subjects had a mean age of 51.9±12.0 years and included 812 (37.4%) males and 1,357 (62.6%) females. Of the subjects, 726 (33.5%) were overweight, 226 (10.4%) were obese, 272 (12.5%) had diabetes, 738 (34.0%) had hypertension, and 1,156 (53.3%) had metabolic syndrome. After controlling for the effects of potential confounders, multivariate analyses found that age ([beta] = 0.06, P = 0.008), sex ([beta] = 1.33, P = 0.015), mean arterial blood pressure ([beta] = -0.12, P<0.001), high-sensitivity C-reactive protein ([beta] = -0.22, P = 0.008), and CRVE ([beta] = 0.23, P<0.001) were significantly associated with CRAE. Age ([beta] = -0.0012, P<0.001), BP classification (prehypertension: [beta] = -0.0075, P = 0.014; hypertension: [beta] = -0.0131, P = 0.002), and hypertension history ([beta] = -0.0007, P = 0.009) were significantly associated with D(f). D(f) exhibits a stronger association with BP than CRAE. Thus, D(f) may become a useful indicator of cardiovascular risk. Background This study aimed to investigate the correlation between quantitative retinal vascular parameters such as central retinal arteriolar equivalent (CRAE) and retinal vascular fractal dimension (D(f)), and cardiovascular risk factors in the Chinese Han population residing in the in islands of southeast China. Methodology/Principle Findings In this cross-sectional study, fundus photographs were collected and semi-automated analysis software was used to analyze retinal vessel diameters and fractal dimensions. Cardiovascular risk factors such as relevant medical history, blood pressure (BP), lipids, and blood glucose data were collected. Subjects had a mean age of 51.9±12.0 years and included 812 (37.4%) males and 1,357 (62.6%) females. Of the subjects, 726 (33.5%) were overweight, 226 (10.4%) were obese, 272 (12.5%) had diabetes, 738 (34.0%) had hypertension, and 1,156 (53.3%) had metabolic syndrome. After controlling for the effects of potential confounders, multivariate analyses found that age ([beta] = 0.06, P = 0.008), sex ([beta] = 1.33, P = 0.015), mean arterial blood pressure ([beta] = -0.12, P<0.001), high-sensitivity C-reactive protein ([beta] = -0.22, P = 0.008), and CRVE ([beta] = 0.23, P<0.001) were significantly associated with CRAE. Age ([beta] = -0.0012, P<0.001), BP classification (prehypertension: [beta] = -0.0075, P = 0.014; hypertension: [beta] = -0.0131, P = 0.002), and hypertension history ([beta] = -0.0007, P = 0.009) were significantly associated with D(f). Conclusions/Significance D(f) exhibits a stronger association with BP than CRAE. Thus, D(f) may become a useful indicator of cardiovascular risk. This study aimed to investigate the correlation between quantitative retinal vascular parameters such as central retinal arteriolar equivalent (CRAE) and retinal vascular fractal dimension (D(f)), and cardiovascular risk factors in the Chinese Han population residing in the in islands of southeast China. In this cross-sectional study, fundus photographs were collected and semi-automated analysis software was used to analyze retinal vessel diameters and fractal dimensions. Cardiovascular risk factors such as relevant medical history, blood pressure (BP), lipids, and blood glucose data were collected. Subjects had a mean age of 51.9 ± 12.0 years and included 812 (37.4%) males and 1,357 (62.6%) females. Of the subjects, 726 (33.5%) were overweight, 226 (10.4%) were obese, 272 (12.5%) had diabetes, 738 (34.0%) had hypertension, and 1,156 (53.3%) had metabolic syndrome. After controlling for the effects of potential confounders, multivariate analyses found that age (β = 0.06, P = 0.008), sex (β = 1.33, P = 0.015), mean arterial blood pressure (β = -0.12, P<0.001), high-sensitivity C-reactive protein (β = -0.22, P = 0.008), and CRVE (β = 0.23, P<0.001) were significantly associated with CRAE. Age (β = -0.0012, P < 0.001), BP classification (prehypertension: β = -0.0075, P = 0.014; hypertension: β = -0.0131, P = 0.002), and hypertension history (β = -0.0007, P = 0.009) were significantly associated with D(f). D(f) exhibits a stronger association with BP than CRAE. Thus, D(f) may become a useful indicator of cardiovascular risk. Background This study aimed to investigate the correlation between quantitative retinal vascular parameters such as central retinal arteriolar equivalent (CRAE) and retinal vascular fractal dimension (D(f)), and cardiovascular risk factors in the Chinese Han population residing in the in islands of southeast China. Methodology/Principle Findings In this cross-sectional study, fundus photographs were collected and semi-automated analysis software was used to analyze retinal vessel diameters and fractal dimensions. Cardiovascular risk factors such as relevant medical history, blood pressure (BP), lipids, and blood glucose data were collected. Subjects had a mean age of 51.9±12.0 years and included 812 (37.4%) males and 1,357 (62.6%) females. Of the subjects, 726 (33.5%) were overweight, 226 (10.4%) were obese, 272 (12.5%) had diabetes, 738 (34.0%) had hypertension, and 1,156 (53.3%) had metabolic syndrome. After controlling for the effects of potential confounders, multivariate analyses found that age ( β = 0.06, P = 0.008), sex ( β = 1.33, P = 0.015), mean arterial blood pressure ( β = −0.12, P <0.001), high-sensitivity C-reactive protein ( β = −0.22, P = 0.008), and CRVE ( β = 0.23, P <0.001) were significantly associated with CRAE. Age ( β = −0.0012, P <0.001), BP classification (prehypertension: β = −0.0075, P = 0.014; hypertension: β = −0.0131, P = 0.002), and hypertension history ( β = −0.0007, P = 0.009) were significantly associated with D(f). Conclusions/Significance D(f) exhibits a stronger association with BP than CRAE. Thus, D(f) may become a useful indicator of cardiovascular risk. BACKGROUND: This study aimed to investigate the correlation between quantitative retinal vascular parameters such as central retinal arteriolar equivalent (CRAE) and retinal vascular fractal dimension (D(f)), and cardiovascular risk factors in the Chinese Han population residing in the in islands of southeast China. METHODOLOGY/PRINCIPLE FINDINGS: In this cross-sectional study, fundus photographs were collected and semi-automated analysis software was used to analyze retinal vessel diameters and fractal dimensions. Cardiovascular risk factors such as relevant medical history, blood pressure (BP), lipids, and blood glucose data were collected. Subjects had a mean age of 51.9 ± 12.0 years and included 812 (37.4%) males and 1,357 (62.6%) females. Of the subjects, 726 (33.5%) were overweight, 226 (10.4%) were obese, 272 (12.5%) had diabetes, 738 (34.0%) had hypertension, and 1,156 (53.3%) had metabolic syndrome. After controlling for the effects of potential confounders, multivariate analyses found that age (β = 0.06, P = 0.008), sex (β = 1.33, P = 0.015), mean arterial blood pressure (β = -0.12, P<0.001), high-sensitivity C-reactive protein (β = -0.22, P = 0.008), and CRVE (β = 0.23, P<0.001) were significantly associated with CRAE. Age (β = -0.0012, P < 0.001), BP classification (prehypertension: β = -0.0075, P = 0.014; hypertension: β = -0.0131, P = 0.002), and hypertension history (β = -0.0007, P = 0.009) were significantly associated with D(f). CONCLUSIONS/SIGNIFICANCE: D(f) exhibits a stronger association with BP than CRAE. Thus, D(f) may become a useful indicator of cardiovascular risk. Background This study aimed to investigate the correlation between quantitative retinal vascular parameters such as central retinal arteriolar equivalent (CRAE) and retinal vascular fractal dimension (D(f)), and cardiovascular risk factors in the Chinese Han population residing in the in islands of southeast China. Methodology/Principle Findings In this cross-sectional study, fundus photographs were collected and semi-automated analysis software was used to analyze retinal vessel diameters and fractal dimensions. Cardiovascular risk factors such as relevant medical history, blood pressure (BP), lipids, and blood glucose data were collected. Subjects had a mean age of 51.9±12.0 years and included 812 (37.4%) males and 1,357 (62.6%) females. Of the subjects, 726 (33.5%) were overweight, 226 (10.4%) were obese, 272 (12.5%) had diabetes, 738 (34.0%) had hypertension, and 1,156 (53.3%) had metabolic syndrome. After controlling for the effects of potential confounders, multivariate analyses found that age (β = 0.06, P = 0.008), sex (β = 1.33, P = 0.015), mean arterial blood pressure (β = −0.12, P<0.001), high-sensitivity C-reactive protein (β = −0.22, P = 0.008), and CRVE (β = 0.23, P<0.001) were significantly associated with CRAE. Age (β = −0.0012, P<0.001), BP classification (prehypertension: β = −0.0075, P = 0.014; hypertension: β = −0.0131, P = 0.002), and hypertension history (β = −0.0007, P = 0.009) were significantly associated with D(f). Conclusions/Significance D(f) exhibits a stronger association with BP than CRAE. Thus, D(f) may become a useful indicator of cardiovascular risk. |
| Audience | Academic |
| Author | Yuan, Yin Zhu, Pengli Chen, Falin Huang, Feng Lin, Fan Gao, Zhonghai Li, Qiaowei |
| AuthorAffiliation | University of Campinas, Brazil 2 Department of Ophthalmology, Fujian Provincial Hospital, Fuzhou, China 3 Clinical Laboratory Center, Fujian Provincial Hospital, Fuzhou, China 1 Department of Geriatric Medicine, Fujian Provincial Hospital, Fujian Provincial Institute of Clinical Geriatrics, Fujian Medical University, Fuzhou, China |
| AuthorAffiliation_xml | – name: 2 Department of Ophthalmology, Fujian Provincial Hospital, Fuzhou, China – name: 3 Clinical Laboratory Center, Fujian Provincial Hospital, Fuzhou, China – name: 1 Department of Geriatric Medicine, Fujian Provincial Hospital, Fujian Provincial Institute of Clinical Geriatrics, Fujian Medical University, Fuzhou, China – name: University of Campinas, Brazil |
| Author_xml | – sequence: 1 givenname: Pengli surname: Zhu fullname: Zhu, Pengli – sequence: 2 givenname: Feng surname: Huang fullname: Huang, Feng – sequence: 3 givenname: Fan surname: Lin fullname: Lin, Fan – sequence: 4 givenname: Qiaowei surname: Li fullname: Li, Qiaowei – sequence: 5 givenname: Yin surname: Yuan fullname: Yuan, Yin – sequence: 6 givenname: Zhonghai surname: Gao fullname: Gao, Zhonghai – sequence: 7 givenname: Falin surname: Chen fullname: Chen, Falin |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/25188273$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNk11v0zAUhiM0xLbCP0AQCQnBRYudxPngAmkUCpUmDZWxW8t2TloXJy62s8G_5_RjUztNCOUi8cnzvj5-5XMaHXW2gyh6TsmIpgV9t7S964QZrbA8IpTkjNFH0Qmt0mSYJyQ92vs-jk69XxLC0jLPn0THCaNlmRTpSXRzuYB4BkYEbTu_0KvYNrgOGq3jK_AeTPxJixYCOB-Lro4nTqgg1tUWOr9WxTc6LOKPxto6_uZQ0zvYoGPham2vhVe9ES6eaf8znqDaOv80etwI4-HZ7j2Ifkw-X46_Ds8vvkzHZ-dDlVdJGNapIBIoyEpWBcnLTFKZQFnUCSNS1oKwjEFFZFlLyrKyAKqaBOpSSVVkUkE6iF5ufVfGer7LzHPKcoysStMMiemWqK1Y8pXTrXB_uBWabwrWzblwQSsDHDMjgEGTNJEZJNhOWVSENUVeCCaLGr0-7HbrZQu1gi44YQ5MD_90esHn9ppn2H2B_QyiNzsDZ3_14ANvtVdgjOjA9tu-WVmyjCD66h768Ol21FzgAXTXWNxXrU35WUbzqmAYK1KjByh8ami1wgvWaKwfCN4eCJAJ8DvMRe89n36f_T97cXXIvt5jFyBMWHhr-s3tPARf7Cd9F_HtzUYg2wLKWe8dNHcIJXw9QLdx8fUA8d0Aoez9PZnSYTMcmIg2_xb_BU-ZIX0 |
| CitedBy_id | crossref_primary_10_1371_journal_pone_0241055 crossref_primary_10_1371_journal_pone_0136678 crossref_primary_10_1007_s13042_021_01419_0 crossref_primary_10_2337_dc21_1124 crossref_primary_10_1097_HJH_0000000000001408 crossref_primary_10_1007_s00417_023_06117_x crossref_primary_10_1371_journal_pone_0194694 crossref_primary_10_1159_000527765 crossref_primary_10_52547_jist_9_34_79 crossref_primary_10_3390_pr6120254 crossref_primary_10_1038_s41597_023_02704_z crossref_primary_10_1111_opo_12967 crossref_primary_10_3389_fphys_2022_824646 crossref_primary_10_1038_s41598_021_02329_5 crossref_primary_10_1038_s41598_022_15710_9 crossref_primary_10_1155_2017_2562759 crossref_primary_10_3390_vision6030045 crossref_primary_10_1016_j_artres_2015_01_001 crossref_primary_10_1016_j_compbiomed_2025_109941 crossref_primary_10_1371_journal_pone_0254918 crossref_primary_10_3389_fopht_2024_1332197 crossref_primary_10_1167_tvst_8_3_60 crossref_primary_10_1016_j_mvr_2019_103966 crossref_primary_10_1371_journal_pone_0170014 crossref_primary_10_1186_s12882_021_02273_6 crossref_primary_10_3389_fmed_2022_925756 crossref_primary_10_1111_aos_14598 crossref_primary_10_1111_aos_15047 |
| Cites_doi | 10.1016/j.atherosclerosis.2012.10.034 10.1111/j.1442-9071.2007.01627.x 10.1097/00019501-200602000-00002 10.1016/j.ajo.2012.04.016 10.1177/193229681200600315 10.1111/j.1445-5994.2011.02470.x 10.1016/S0140-6736(05)67402-8 10.1016/j.ejheart.2006.10.019 10.1212/01.wnl.0000210533.24338.ea 10.1056/NEJMra0800885 10.1002/ana.22011 10.1016/j.media.2009.05.003 10.1016/S0140-6736(01)06253-5 10.1161/HYPERTENSIONAHA.111.189142 10.1001/archopht.126.10.1404 10.1161/CIR.0b013e31823ac046 10.1076/ceyr.27.3.143.16049 10.1016/j.ophtha.2010.08.045 10.1001/jama.289.19.2560 10.1016/j.neurobiolaging.2010.04.010 10.1161/01.HYP.0000140772.40322.ec 10.1167/iovs.03-1390 10.1097/HJH.0b013e328347266c 10.1093/eurheartj/ehm221 10.1016/j.ophtha.2008.05.029 10.1212/WNL.0b013e31821a7d7d 10.1007/BF00919281 10.1159/000337252 10.1016/S0161-6420(03)00084-8 10.1136/bmj.38124.682523.55 10.1016/S0161-6420(02)01931-0 10.2337/dc08-1233 10.1093/eurheartj/ehq431 10.1016/j.ophtha.2006.02.052 10.1016/j.diabres.2011.07.032 10.1038/sj.jhh.1002193 10.1016/j.atherosclerosis.2013.04.019 10.3109/08037051.2012.645336 10.1097/01.hjh.0000125455.28861.3f 10.1001/archinte.166.21.2388 10.1167/iovs.05-1539 10.2337/dc09-0719 10.1093/ndt/gfq007 10.1167/iovs.07-1450 10.7326/0003-4819-140-4-200402170-00006 |
| ContentType | Journal Article |
| Copyright | COPYRIGHT 2014 Public Library of Science 2014 Zhu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2014 Zhu et al 2014 Zhu et al |
| Copyright_xml | – notice: COPYRIGHT 2014 Public Library of Science – notice: 2014 Zhu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: 2014 Zhu et al 2014 Zhu et al |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM IOV ISR 3V. 7QG 7QL 7QO 7RV 7SN 7SS 7T5 7TG 7TM 7U9 7X2 7X7 7XB 88E 8AO 8C1 8FD 8FE 8FG 8FH 8FI 8FJ 8FK ABJCF ABUWG AEUYN AFKRA ARAPS ATCPS AZQEC BBNVY BENPR BGLVJ BHPHI C1K CCPQU D1I DWQXO FR3 FYUFA GHDGH GNUQQ H94 HCIFZ K9. KB. KB0 KL. L6V LK8 M0K M0S M1P M7N M7P M7S NAPCQ P5Z P62 P64 PATMY PDBOC PHGZM PHGZT PIMPY PJZUB PKEHL PPXIY PQEST PQGLB PQQKQ PQUKI PRINS PTHSS PYCSY RC3 7X8 5PM DOA |
| DOI | 10.1371/journal.pone.0106551 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Gale In Context: Opposing Viewpoints Gale In Context: Science ProQuest Central (Corporate) Animal Behavior Abstracts Bacteriology Abstracts (Microbiology B) Biotechnology Research Abstracts Nursing & Allied Health Database Ecology Abstracts Entomology Abstracts (Full archive) Immunology Abstracts Meteorological & Geoastrophysical Abstracts Nucleic Acids Abstracts Virology and AIDS Abstracts Agricultural Science Collection Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) ProQuest Pharma Collection Public Health Database Technology Research Database ProQuest SciTech Collection ProQuest Technology Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) Materials Science & Engineering Collection ProQuest Central (Alumni) ProQuest One Sustainability ProQuest Central UK/Ireland Advanced Technologies & Aerospace Collection Agricultural & Environmental Science Collection ProQuest Central Essentials Biological Science Collection ProQuest Central Technology Collection Natural Science Collection Environmental Sciences and Pollution Management ProQuest One Community College ProQuest Materials Science Collection ProQuest Central Korea Engineering Research Database ProQuest Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student AIDS and Cancer Research Abstracts SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) Materials Science Database Nursing & Allied Health Database (Alumni Edition) Meteorological & Geoastrophysical Abstracts - Academic ProQuest Engineering Collection Biological Sciences Agricultural Science Database ProQuest Health & Medical Collection Medical Database Algology Mycology and Protozoology Abstracts (Microbiology C) Biological Science Database Engineering Database Nursing & Allied Health Premium Advanced Technologies & Aerospace Database ProQuest Advanced Technologies & Aerospace Collection Biotechnology and BioEngineering Abstracts Environmental Science Database Materials Science Collection ProQuest Central Premium ProQuest One Academic (New) Publicly Available Content Database ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Applied & Life Sciences ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China Engineering Collection Environmental Science Collection Genetics Abstracts MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journal Collection |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Agricultural Science Database Publicly Available Content Database ProQuest Central Student ProQuest Advanced Technologies & Aerospace Collection ProQuest Central Essentials Nucleic Acids Abstracts SciTech Premium Collection ProQuest Central China Environmental Sciences and Pollution Management ProQuest One Applied & Life Sciences ProQuest One Sustainability Health Research Premium Collection Meteorological & Geoastrophysical Abstracts Natural Science Collection Health & Medical Research Collection Biological Science Collection ProQuest Central (New) ProQuest Medical Library (Alumni) Engineering Collection Advanced Technologies & Aerospace Collection Engineering Database Virology and AIDS Abstracts ProQuest Biological Science Collection ProQuest One Academic Eastern Edition Agricultural Science Collection ProQuest Hospital Collection ProQuest Technology Collection Health Research Premium Collection (Alumni) Biological Science Database Ecology Abstracts ProQuest Hospital Collection (Alumni) Biotechnology and BioEngineering Abstracts Environmental Science Collection Entomology Abstracts Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest One Academic UKI Edition Environmental Science Database ProQuest Nursing & Allied Health Source (Alumni) Engineering Research Database ProQuest One Academic Meteorological & Geoastrophysical Abstracts - Academic ProQuest One Academic (New) Technology Collection Technology Research Database ProQuest One Academic Middle East (New) Materials Science Collection ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Natural Science Collection ProQuest Pharma Collection ProQuest Central ProQuest Health & Medical Research Collection Genetics Abstracts ProQuest Engineering Collection Biotechnology Research Abstracts Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Bacteriology Abstracts (Microbiology B) Algology Mycology and Protozoology Abstracts (Microbiology C) Agricultural & Environmental Science Collection AIDS and Cancer Research Abstracts Materials Science Database ProQuest Materials Science Collection ProQuest Public Health ProQuest Nursing & Allied Health Source ProQuest SciTech Collection Advanced Technologies & Aerospace Database ProQuest Medical Library Animal Behavior Abstracts Materials Science & Engineering Collection Immunology Abstracts ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE Agricultural Science Database |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 4 dbid: 8FG name: ProQuest Technology Collection url: https://search.proquest.com/technologycollection1 sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Sciences (General) Medicine |
| DocumentTitleAlternate | D(f) for Hypertension Predicting |
| EISSN | 1932-6203 |
| ExternalDocumentID | 1560109334 oai_doaj_org_article_8820e065032b4e268487905f767a5b7d PMC4154709 3423268031 A416975706 25188273 10_1371_journal_pone_0106551 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GeographicLocations | China Blue Mountains |
| GeographicLocations_xml | – name: China – name: Blue Mountains |
| GroupedDBID | --- 123 29O 2WC 53G 5VS 7RV 7X2 7X7 7XC 88E 8AO 8C1 8CJ 8FE 8FG 8FH 8FI 8FJ A8Z AAFWJ AAUCC AAWOE AAYXX ABDBF ABIVO ABJCF ABUWG ACGFO ACIHN ACIWK ACPRK ACUHS ADBBV ADRAZ AEAQA AENEX AEUYN AFKRA AFPKN AFRAH AHMBA ALIPV ALMA_UNASSIGNED_HOLDINGS AOIJS APEBS ARAPS ATCPS BAWUL BBNVY BCNDV BENPR BGLVJ BHPHI BKEYQ BPHCQ BVXVI BWKFM CCPQU CITATION CS3 D1I D1J D1K DIK DU5 E3Z EAP EAS EBD EMOBN ESX EX3 F5P FPL FYUFA GROUPED_DOAJ GX1 HCIFZ HH5 HMCUK HYE IAO IEA IGS IHR IHW INH INR IOV IPY ISE ISR ITC K6- KB. KQ8 L6V LK5 LK8 M0K M1P M48 M7P M7R M7S M~E NAPCQ O5R O5S OK1 OVT P2P P62 PATMY PDBOC PHGZM PHGZT PIMPY PQQKQ PROAC PSQYO PTHSS PYCSY RNS RPM SV3 TR2 UKHRP WOQ WOW ~02 ~KM CGR CUY CVF ECM EIF IPNFZ NPM PJZUB PPXIY PQGLB PV9 RIG RZL BBORY PMFND 3V. 7QG 7QL 7QO 7SN 7SS 7T5 7TG 7TM 7U9 7XB 8FD 8FK AZQEC C1K DWQXO FR3 GNUQQ H94 K9. KL. M7N P64 PKEHL PQEST PQUKI PRINS RC3 7X8 PUEGO 5PM AAPBV ABPTK |
| ID | FETCH-LOGICAL-c692t-d3a0be1eb9b970684b1b2e87d250bbda0545e90b8db15487e1cf2ed8cbc74bce3 |
| IEDL.DBID | 7X7 |
| ISSN | 1932-6203 |
| IngestDate | Sun Oct 01 00:11:38 EDT 2023 Wed Aug 27 01:13:00 EDT 2025 Thu Aug 21 18:43:12 EDT 2025 Sun Aug 24 03:56:41 EDT 2025 Sat Aug 16 22:22:25 EDT 2025 Tue Jun 17 21:27:27 EDT 2025 Tue Jun 10 20:23:00 EDT 2025 Fri Jun 27 04:56:24 EDT 2025 Fri Jun 27 04:09:17 EDT 2025 Thu May 22 20:06:00 EDT 2025 Mon Jul 21 05:39:39 EDT 2025 Tue Jul 01 03:38:18 EDT 2025 Thu Apr 24 22:56:10 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 9 |
| Language | English |
| License | This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. Creative Commons Attribution License |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c692t-d3a0be1eb9b970684b1b2e87d250bbda0545e90b8db15487e1cf2ed8cbc74bce3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 Competing Interests: The authors have declared that no competing interests exist. Conceived and designed the experiments: PZ. Performed the experiments: FH FL. Analyzed the data: QL YY. Contributed reagents/materials/analysis tools: ZG FC. Wrote the paper: FH QL. |
| OpenAccessLink | https://www.proquest.com/docview/1560109334?pq-origsite=%requestingapplication% |
| PMID | 25188273 |
| PQID | 1560109334 |
| PQPubID | 1436336 |
| ParticipantIDs | plos_journals_1560109334 doaj_primary_oai_doaj_org_article_8820e065032b4e268487905f767a5b7d pubmedcentral_primary_oai_pubmedcentral_nih_gov_4154709 proquest_miscellaneous_1560588540 proquest_journals_1560109334 gale_infotracmisc_A416975706 gale_infotracacademiconefile_A416975706 gale_incontextgauss_ISR_A416975706 gale_incontextgauss_IOV_A416975706 gale_healthsolutions_A416975706 pubmed_primary_25188273 crossref_primary_10_1371_journal_pone_0106551 crossref_citationtrail_10_1371_journal_pone_0106551 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2014-09-04 |
| PublicationDateYYYYMMDD | 2014-09-04 |
| PublicationDate_xml | – month: 09 year: 2014 text: 2014-09-04 day: 04 |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States – name: San Francisco – name: San Francisco, USA |
| PublicationTitle | PloS one |
| PublicationTitleAlternate | PLoS One |
| PublicationYear | 2014 |
| Publisher | Public Library of Science Public Library of Science (PLoS) |
| Publisher_xml | – name: Public Library of Science – name: Public Library of Science (PLoS) |
| References | CY Cheung (ref7) 2012; 60 SW Lim (ref16) 2009; 32 TY Wong (ref5) 2006; 47 TY Wong (ref42) 2003; 110 H Gullu (ref48) 2007; 9 TY Wong (ref41) 2001; 358 R Lopes (ref14) 2009; 13 G Liew (ref21) 2011; 32 MD Knudtson (ref31) 2003; 27 Y Yuan (ref49) 2011; 24 ACT de (ref47) 2007; 21 CY Cheung (ref8) 2011; 29 TY Wong (ref35) 2003; 110 W Smith (ref39) 2004; 44 Ş Ţălu (ref13) 2013; 5 R Crosby-Nwaobi (ref30) 2012; 228 TY Wong (ref4) 2006; 166 MK Ikram (ref34) 2004; 45 TY Wong (ref40) 2004; 140 ref9 CY Cheung (ref52) 2012; 6 VL Roger (ref6) 2012; 125 R Kawasaki (ref38) 2006; 113 ref36 JG Fodor (ref25) 1973; 108 TY Wong (ref33) 2004; 329 F Huang (ref26) 2013; 41 FS Torres (ref1) 2013; 229 CL Avery (ref12) 2012; 225 N Cheung (ref19) 2010; 68 N Cheung (ref17) 2009; 32 A Kirkutis (ref24) 2004; 47 H Leung (ref43) 2004; 22 D Erdogan (ref46) 2006; 17 TY Wong (ref2) 2002; 287 C Sun (ref23) 2008; 49 CC Sng (ref18) 2010; 25 JJ Wang (ref10) 2007; 28 KG Alberti (ref27) 2005; 366 MS Roy (ref11) 2012; 130 CY Cheung (ref44) 2011; 118 DI Feig (ref45) 2008; 359 Y Yuan (ref50) 2012; 42 S Wang (ref22) 2007; 35 AV Chobanian (ref28) 2003; 289 ref29 R Gepstein (ref37) 2012; 21 G Liew (ref32) 2008; 126 MK Ikram (ref3) 2006; 66 R Kawasaki (ref20) 2011; 76 AS Tsai (ref51) 2011; 94 G Liew (ref15) 2008; 115 A Daxer (ref53) 1993; 231 20472327 - Neurobiol Aging. 2012 Jan;33(1):194.e1-4 18436813 - Invest Ophthalmol Vis Sci. 2008 May;49(5):1784-90 12750093 - Ophthalmology. 2003 May;110(5):933-40 12748199 - JAMA. 2003 May 21;289(19):2560-72 14970147 - Ann Intern Med. 2004 Feb 17;140(4):248-55 21576694 - Neurology. 2011 May 17;76(20):1766-7 14562179 - Curr Eye Res. 2003 Sep;27(3):143-9 15302843 - Hypertension. 2004 Oct;44(4):442-7 17626032 - Eur Heart J. 2007 Aug;28(16):1984-92 23045470 - Hypertension. 2012 Nov;60(5):1094-103 16723443 - Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2341-50 22768891 - J Diabetes Sci Technol. 2012 May;6(3):595-605 21864932 - Diabetes Res Clin Pract. 2011 Nov;94(2):291-8 18692247 - Ophthalmology. 2008 Nov;115(11):1951-6 22179539 - Circulation. 2012 Jan 3;125(1):e2-e220 21565686 - Biomed Environ Sci. 2011 Apr;24(2):146-54 21558958 - J Hypertens. 2011 Jul;29(7):1380-91 12689883 - Ophthalmology. 2003 Apr;110(4):658-66 11597667 - Lancet. 2001 Oct 6;358(9288):1134-40 21146228 - Ophthalmology. 2011 May;118(5):812-8 16182882 - Lancet. 2005 Sep 24-30;366(9491):1059-62 11879113 - JAMA. 2002 Mar 6;287(9):1153-9 15175230 - BMJ. 2004 Jul 10;329(7457):79 22517193 - Ophthalmologica. 2012;228(2):84-92 23102597 - Atherosclerosis. 2012 Dec;225(2):412-7 15223786 - Invest Ophthalmol Vis Sci. 2004 Jul;45(7):2129-34 4704904 - Can Med Assoc J. 1973 Jun 2;108(11):1365-8 24377896 - Zhonghua Xin Xue Guan Bing Za Zhi. 2013 Oct;41(10):876-81 22840482 - Am J Ophthalmol. 2012 Oct;154(4):663-674.e1 16374135 - Coron Artery Dis. 2006 Feb;17(1):7-14 17130394 - Arch Intern Med. 2006 Nov 27;166(21):2388-94 18946066 - N Engl J Med. 2008 Oct 23;359(17):1811-21 15257178 - J Hypertens. 2004 Aug;22(8):1543-9 18173406 - Clin Experiment Ophthalmol. 2007 Dec;35(9):800-7 21525493 - Diabetes Care. 2011 May;34(5):e53; author reply e54 17169608 - Eur J Heart Fail. 2007 May;9(5):466-8 18835945 - Diabetes Care. 2009 Jan;32(1):106-10 19535282 - Med Image Anal. 2009 Aug;13(4):634-49 19690082 - Diabetes Care. 2009 Nov;32(11):2081-3 16877076 - Ophthalmology. 2006 Aug;113(8):1378-84 22652842 - Arch Ophthalmol. 2012 May;130(5):561-7 21395957 - Intern Med J. 2012 Sep;42(9):1014-22 15633617 - Proc West Pharmacol Soc. 2004;47:71-5 23664203 - Atherosclerosis. 2013 Jul;229(1):134-8 22263560 - Blood Press. 2012 Jun;21(3):191-6 18852419 - Arch Ophthalmol. 2008 Oct;126(10):1404-10 20582985 - Ann Neurol. 2010 Jul;68(1):107-11 20124213 - Nephrol Dial Transplant. 2010 Jul;25(7):2252-8 16682664 - Neurology. 2006 May 9;66(9):1339-43 8299974 - Graefes Arch Clin Exp Ophthalmol. 1993 Dec;231(12):681-6 17541391 - J Hum Hypertens. 2007 Aug;21(8):610-5 21138936 - Eur Heart J. 2011 Feb;32(4):422-9 |
| References_xml | – volume: 225 start-page: 412 year: 2012 ident: ref12 article-title: Impact of long-term measures of glucose and blood pressure on the retinal microvasculature publication-title: Atherosclerosis doi: 10.1016/j.atherosclerosis.2012.10.034 – volume: 5 start-page: 52 year: 2013 ident: ref13 article-title: Characterization of retinal vessel networks in human retinal imagery using quantitative descriptors publication-title: Human Vet Med – volume: 35 start-page: 800 year: 2007 ident: ref22 article-title: Retinal vessel diameter in normal and glaucomatous eyes: the Beijing eye study publication-title: Clin Experiment Ophthalmol doi: 10.1111/j.1442-9071.2007.01627.x – volume: 17 start-page: 7 year: 2006 ident: ref46 article-title: Coronary flow reserve and coronary microvascular functions are strongly related to serum uric acid concentrations in healthy adults publication-title: Coron Artery Dis doi: 10.1097/00019501-200602000-00002 – ident: ref9 doi: 10.1016/j.ajo.2012.04.016 – volume: 6 start-page: 595 year: 2012 ident: ref52 article-title: Retinal vascular geometry in Asian persons with diabetes and retinopathy publication-title: J Diabetes Sci Technol doi: 10.1177/193229681200600315 – volume: 42 start-page: 1014 year: 2012 ident: ref50 article-title: Retinal Vascular Caliber and Metabolic Syndrome in a Chinese Population publication-title: Intern Med J doi: 10.1111/j.1445-5994.2011.02470.x – volume: 366 start-page: 1059 year: 2005 ident: ref27 article-title: The metabolic syndrome–a new worldwide definition publication-title: Lancet doi: 10.1016/S0140-6736(05)67402-8 – volume: 9 start-page: 466 year: 2007 ident: ref48 article-title: Elevated serum uric acid levels impair coronary microvascular function in patients with idiopathic dilated cardiomyopathy publication-title: Eur J Heart Fail doi: 10.1016/j.ejheart.2006.10.019 – volume: 66 start-page: 1339 year: 2006 ident: ref3 article-title: Retinal vessel diameters and risk of stroke: the Rotterdam Study publication-title: Neurology doi: 10.1212/01.wnl.0000210533.24338.ea – volume: 108 start-page: 1365 year: 1973 ident: ref25 article-title: An epidemiologic study of hypertension in Newfoundland publication-title: Can Med Assoc J – volume: 359 start-page: 1811 year: 2008 ident: ref45 article-title: Uric acid and cardiovascular risk publication-title: N Engl J Med doi: 10.1056/NEJMra0800885 – volume: 47 start-page: 71 year: 2004 ident: ref24 article-title: Prevalence of hypertension in Lithuanian mariners publication-title: Proc West Pharmacol Soc – volume: 68 start-page: 107 year: 2010 ident: ref19 article-title: Retinal fractals and acute lacunar stroke publication-title: Ann Neurol doi: 10.1002/ana.22011 – volume: 13 start-page: 634 year: 2009 ident: ref14 article-title: Fractal and multifractal analysis: a review publication-title: Med Image Anal doi: 10.1016/j.media.2009.05.003 – volume: 358 start-page: 1134 year: 2001 ident: ref41 article-title: Retinal microvascular abnormalities and incident stroke: the Atherosclerosis Risk in Communities Study publication-title: Lancet doi: 10.1016/S0140-6736(01)06253-5 – volume: 60 start-page: 1094 year: 2012 ident: ref7 article-title: Retinal microvasculature as a model to study the manifestations of hypertension publication-title: Hypertension doi: 10.1161/HYPERTENSIONAHA.111.189142 – volume: 126 start-page: 1404 year: 2008 ident: ref32 article-title: Relative importance of systemic determinants of retinal arteriolar and venular caliber: the atherosclerosis risk in communities study publication-title: Arch Ophthalmol doi: 10.1001/archopht.126.10.1404 – volume: 125 start-page: e2 year: 2012 ident: ref6 article-title: Heart disease and stroke statistics–2012 update: a report from the American Heart Association publication-title: Circulation doi: 10.1161/CIR.0b013e31823ac046 – volume: 27 start-page: 143 year: 2003 ident: ref31 article-title: Revised formulas for summarizing retinal vessel diameters publication-title: Curr Eye Res doi: 10.1076/ceyr.27.3.143.16049 – volume: 118 start-page: 812 year: 2011 ident: ref44 article-title: Retinal vascular tortuosity, blood pressure, and cardiovascular risk factors publication-title: Ophthalmology doi: 10.1016/j.ophtha.2010.08.045 – volume: 289 start-page: 2560 year: 2003 ident: ref28 article-title: The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report publication-title: JAMA doi: 10.1001/jama.289.19.2560 – ident: ref36 doi: 10.1016/j.neurobiolaging.2010.04.010 – volume: 44 start-page: 442 year: 2004 ident: ref39 article-title: Retinal arteriolar narrowing is associated with 5-year incident severe hypertension: the Blue Mountains Eye Study publication-title: Hypertension doi: 10.1161/01.HYP.0000140772.40322.ec – volume: 45 start-page: 2129 year: 2004 ident: ref34 article-title: Are retinal arteriolar or venular diameters associated with markers for cardiovascular disorders? The Rotterdam Study publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.03-1390 – volume: 29 start-page: 1380 year: 2011 ident: ref8 article-title: Quantitative and qualitative retinal microvascular characteristics and blood pressure publication-title: J Hypertens doi: 10.1097/HJH.0b013e328347266c – ident: ref29 – volume: 28 start-page: 1984 year: 2007 ident: ref10 article-title: Retinal vessel diameter and cardiovascular mortality: pooled data analysis from two older populations publication-title: Eur Heart J doi: 10.1093/eurheartj/ehm221 – volume: 115 start-page: 1951 year: 2008 ident: ref15 article-title: The retinal vasculature as a fractal: methodology, reliability, and relationship to blood pressure publication-title: Ophthalmology doi: 10.1016/j.ophtha.2008.05.029 – volume: 76 start-page: 1766 year: 2011 ident: ref20 article-title: Fractal dimension of the retinal vasculature and risk of stroke: a nested case-control study publication-title: Neurology doi: 10.1212/WNL.0b013e31821a7d7d – volume: 231 start-page: 681 year: 1993 ident: ref53 article-title: Characterisation of the neovascularisation process in diabetic retinopathy by means of fractal geometry: diagnostic implications publication-title: Graefes Arch Clin Exp Ophthalmol doi: 10.1007/BF00919281 – volume: 228 start-page: 84 year: 2012 ident: ref30 article-title: Retinal vascular calibre, geometry and progression of diabetic retinopathy in type 2 diabetes mellitus publication-title: Ophthalmologica doi: 10.1159/000337252 – volume: 110 start-page: 933 year: 2003 ident: ref42 article-title: Retinal microvascular abnormalities and 10-year cardiovascular mortality: a population-based case-control study publication-title: Ophthalmology doi: 10.1016/S0161-6420(03)00084-8 – volume: 329 start-page: 79 year: 2004 ident: ref33 article-title: Prospective cohort study of retinal vessel diameters and risk of hypertension publication-title: BMJ doi: 10.1136/bmj.38124.682523.55 – volume: 110 start-page: 658 year: 2003 ident: ref35 article-title: The prevalence and risk factors of retinal microvascular abnormalities in older persons: The Cardiovascular Health Study publication-title: Ophthalmology doi: 10.1016/S0161-6420(02)01931-0 – volume: 32 start-page: 106 year: 2009 ident: ref17 article-title: Quantitative assessment of early diabetic retinopathy using fractal analysis publication-title: Diabetes Care doi: 10.2337/dc08-1233 – volume: 32 start-page: 422 year: 2011 ident: ref21 article-title: Fractal analysis of retinal microvasculature and coronary heart disease mortality publication-title: Eur Heart J doi: 10.1093/eurheartj/ehq431 – volume: 113 start-page: 1378 year: 2006 ident: ref38 article-title: Cardiovascular risk factors and retinal microvascular signs in an adult Japanese population: the Funagata Study publication-title: Ophthalmology doi: 10.1016/j.ophtha.2006.02.052 – volume: 41 start-page: 876 year: 2013 ident: ref26 article-title: [Cardiovascular disease risk and vascular damage status in pre- and hypertension population in coastal areas of Fujian province] publication-title: Zhonghua Xin Xue Guan Bing Za Zhi – volume: 94 start-page: 291 year: 2011 ident: ref51 article-title: Differential association of retinal arteriolar and venular caliber with diabetes and retinopathy publication-title: Diabetes Res Clin Pract doi: 10.1016/j.diabres.2011.07.032 – volume: 21 start-page: 610 year: 2007 ident: ref47 article-title: Serum uric acid is associated with microvascular function in hypertensive individuals publication-title: J Hum Hypertens doi: 10.1038/sj.jhh.1002193 – volume: 287 start-page: 1153 year: 2002 ident: ref2 article-title: Retinal arteriolar narrowing and risk of coronary heart disease in men and women. The Atherosclerosis Risk in Communities Study publication-title: JAMA – volume: 229 start-page: 134 year: 2013 ident: ref1 article-title: Association between carotid intima-media thickness and retinal arteriolar and venular diameter in patients with hypertension: a cross-sectional study publication-title: Atherosclerosis doi: 10.1016/j.atherosclerosis.2013.04.019 – volume: 21 start-page: 191 year: 2012 ident: ref37 article-title: Association of retinal microvascular caliber with blood pressure levels publication-title: Blood Press doi: 10.3109/08037051.2012.645336 – volume: 22 start-page: 1543 year: 2004 ident: ref43 article-title: Impact of current and past blood pressure on retinal arteriolar diameter in an older population publication-title: J Hypertens doi: 10.1097/01.hjh.0000125455.28861.3f – volume: 130 start-page: 561 year: 2012 ident: ref11 article-title: Relationship of retinal vessel caliber to cardiovascular disease and mortality in African Americans with type 1 diabetes mellitus publication-title: Arch Ophthalmol – volume: 166 start-page: 2388 year: 2006 ident: ref4 article-title: Quantitative retinal venular caliber and risk of cardiovascular disease in older persons: the cardiovascular health study publication-title: Arch Intern Med doi: 10.1001/archinte.166.21.2388 – volume: 47 start-page: 2341 year: 2006 ident: ref5 article-title: Retinal vascular caliber, cardiovascular risk factors, and inflammation: the multi-ethnic study of atherosclerosis (MESA) publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.05-1539 – volume: 32 start-page: 2081 year: 2009 ident: ref16 article-title: Retinal vascular fractal dimension and risk of early diabetic retinopathy: A prospective study of children and adolescents with type 1 diabetes publication-title: Diabetes Care doi: 10.2337/dc09-0719 – volume: 25 start-page: 2252 year: 2010 ident: ref18 article-title: Fractal analysis of the retinal vasculature and chronic kidney disease publication-title: Nephrol Dial Transplant doi: 10.1093/ndt/gfq007 – volume: 49 start-page: 1784 year: 2008 ident: ref23 article-title: Retinal vascular caliber, blood pressure, and cardiovascular risk factors in an Asian population: the Singapore Malay Eye Study publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.07-1450 – volume: 140 start-page: 248 year: 2004 ident: ref40 article-title: Retinal arteriolar diameter and risk for hypertension publication-title: Ann Intern Med doi: 10.7326/0003-4819-140-4-200402170-00006 – volume: 24 start-page: 146 year: 2011 ident: ref49 article-title: Hyperuricemia accompanied with changes in the retinal microcirculation in a Chinese high-risk population for diabetes publication-title: Biomed Environ Sci – reference: 21525493 - Diabetes Care. 2011 May;34(5):e53; author reply e54 – reference: 18692247 - Ophthalmology. 2008 Nov;115(11):1951-6 – reference: 24377896 - Zhonghua Xin Xue Guan Bing Za Zhi. 2013 Oct;41(10):876-81 – reference: 15223786 - Invest Ophthalmol Vis Sci. 2004 Jul;45(7):2129-34 – reference: 21576694 - Neurology. 2011 May 17;76(20):1766-7 – reference: 11597667 - Lancet. 2001 Oct 6;358(9288):1134-40 – reference: 15302843 - Hypertension. 2004 Oct;44(4):442-7 – reference: 22840482 - Am J Ophthalmol. 2012 Oct;154(4):663-674.e1 – reference: 19690082 - Diabetes Care. 2009 Nov;32(11):2081-3 – reference: 23045470 - Hypertension. 2012 Nov;60(5):1094-103 – reference: 17130394 - Arch Intern Med. 2006 Nov 27;166(21):2388-94 – reference: 21558958 - J Hypertens. 2011 Jul;29(7):1380-91 – reference: 23102597 - Atherosclerosis. 2012 Dec;225(2):412-7 – reference: 11879113 - JAMA. 2002 Mar 6;287(9):1153-9 – reference: 16374135 - Coron Artery Dis. 2006 Feb;17(1):7-14 – reference: 16723443 - Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2341-50 – reference: 21565686 - Biomed Environ Sci. 2011 Apr;24(2):146-54 – reference: 12750093 - Ophthalmology. 2003 May;110(5):933-40 – reference: 22768891 - J Diabetes Sci Technol. 2012 May;6(3):595-605 – reference: 14970147 - Ann Intern Med. 2004 Feb 17;140(4):248-55 – reference: 17541391 - J Hum Hypertens. 2007 Aug;21(8):610-5 – reference: 20124213 - Nephrol Dial Transplant. 2010 Jul;25(7):2252-8 – reference: 8299974 - Graefes Arch Clin Exp Ophthalmol. 1993 Dec;231(12):681-6 – reference: 17169608 - Eur J Heart Fail. 2007 May;9(5):466-8 – reference: 18436813 - Invest Ophthalmol Vis Sci. 2008 May;49(5):1784-90 – reference: 20582985 - Ann Neurol. 2010 Jul;68(1):107-11 – reference: 16182882 - Lancet. 2005 Sep 24-30;366(9491):1059-62 – reference: 22517193 - Ophthalmologica. 2012;228(2):84-92 – reference: 18173406 - Clin Experiment Ophthalmol. 2007 Dec;35(9):800-7 – reference: 15257178 - J Hypertens. 2004 Aug;22(8):1543-9 – reference: 17626032 - Eur Heart J. 2007 Aug;28(16):1984-92 – reference: 21138936 - Eur Heart J. 2011 Feb;32(4):422-9 – reference: 12689883 - Ophthalmology. 2003 Apr;110(4):658-66 – reference: 16877076 - Ophthalmology. 2006 Aug;113(8):1378-84 – reference: 23664203 - Atherosclerosis. 2013 Jul;229(1):134-8 – reference: 20472327 - Neurobiol Aging. 2012 Jan;33(1):194.e1-4 – reference: 19535282 - Med Image Anal. 2009 Aug;13(4):634-49 – reference: 21864932 - Diabetes Res Clin Pract. 2011 Nov;94(2):291-8 – reference: 14562179 - Curr Eye Res. 2003 Sep;27(3):143-9 – reference: 4704904 - Can Med Assoc J. 1973 Jun 2;108(11):1365-8 – reference: 18946066 - N Engl J Med. 2008 Oct 23;359(17):1811-21 – reference: 15175230 - BMJ. 2004 Jul 10;329(7457):79 – reference: 21146228 - Ophthalmology. 2011 May;118(5):812-8 – reference: 12748199 - JAMA. 2003 May 21;289(19):2560-72 – reference: 22263560 - Blood Press. 2012 Jun;21(3):191-6 – reference: 18852419 - Arch Ophthalmol. 2008 Oct;126(10):1404-10 – reference: 22652842 - Arch Ophthalmol. 2012 May;130(5):561-7 – reference: 21395957 - Intern Med J. 2012 Sep;42(9):1014-22 – reference: 16682664 - Neurology. 2006 May 9;66(9):1339-43 – reference: 22179539 - Circulation. 2012 Jan 3;125(1):e2-e220 – reference: 15633617 - Proc West Pharmacol Soc. 2004;47:71-5 – reference: 18835945 - Diabetes Care. 2009 Jan;32(1):106-10 |
| SSID | ssj0053866 |
| Score | 2.3440447 |
| Snippet | This study aimed to investigate the correlation between quantitative retinal vascular parameters such as central retinal arteriolar equivalent (CRAE) and... Background This study aimed to investigate the correlation between quantitative retinal vascular parameters such as central retinal arteriolar equivalent... BACKGROUND: This study aimed to investigate the correlation between quantitative retinal vascular parameters such as central retinal arteriolar equivalent... Background This study aimed to investigate the correlation between quantitative retinal vascular parameters such as central retinal arteriolar equivalent... |
| SourceID | plos doaj pubmedcentral proquest gale pubmed crossref |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source |
| StartPage | e106551 |
| SubjectTerms | Age Biology and Life Sciences Blood Blood glucose Blood pressure Blood Pressure - physiology Body mass index Body weight C-reactive protein Cardiovascular disease Cardiovascular diseases Cardiovascular Diseases - pathology China Correlation analysis Cross-Sectional Studies Diabetes Diabetes mellitus Diabetic retinopathy Family medical history Female Females Fisheries Fractal analysis Fractals Geriatrics Glucose Health risks Heart Hemoglobin Hospitals Humans Hypertension Lipids Male Males Medicine Medicine and Health Sciences Metabolic disorders Metabolic syndrome Mortality Multivariate Analysis Overweight Population Retina Retinal Vessels - pathology Risk analysis Risk Factors Stroke Studies Uric acid |
| SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journal Collection dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwELbQnrggyquBAgYhAYe0edixcyyIqiABElDUW-RnW2mbrDa78PeZcZyoQZXKgWs8Xu3OjMefs998JuSVLEolS-9TKzxPmanLVFrNUi69q5jKKimwOfnzl-r4hH065adXrvpCTtggDzw47gAQYOYQR5SFZg61SSRqSnlRCcW1sFh9Yc8bD1NDDYZVXFWxUa4U-UGMy_6qa90-noI4z2cbUdDrn6ryYrXs-usg59_MyStb0dFdcidiSHo4fPcdcsu198hOXKU9fROlpN_eJ78hC-h65LudX6xo5yn2LeL8XygbvqSQIJfIiempai312DWl8OklUtthFsVXtTQQ3GlgzW7XLpiaGZWVIkmdxut7HpCTow8_3h-n8aqF1FR1sUltqTLtcqdrXQsIENO5LpwUFhCS1lYBsOOuzjTEMZxxXG584aw02gimjSsfkkULzt0l1GQ-ry1e4GEYM0JrJYSqlC-8dJpLm5By9Htjog45XoexbMKfawLOI4MbG4xWE6OVkHSatRp0OG6wf4chnWxRRTs8gNxqYm41N-VWQp5jQjRDS-pUC5pDQLG14OCohLwMFqik0SJV50xt-775-PXnPxh9_zYzeh2NfAfuMCq2R8BvQoWumeXezBLqgZkN72L6jl7pmzwcuuuyZDBzTOnrh19Mw_ihSL9rXbcdbLiUgO4T8mhYAZNnC5T0AxCcEDFbGzPXz0fai_MgZA7gkYmsfvw_YvWE3AYsywL9j-2RxWa9dU8BL270s1Aa_gAJFmpa priority: 102 providerName: Directory of Open Access Journals – databaseName: Scholars Portal Journals: Open Access dbid: M48 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3db9MwELemIiFeEBsfKwwwCAl4SJUPJ3YeENoG1UAqSINOe4tsx94quqQ0rYD_njvHjQgqH4-N76r0Puy7-u53hDwTcSJFYm1QcpsGTOdJIErFglRYkzEZZoJjc_LkQ3YyZe_P0_MdspnZ6gXYbE3tcJ7UdDkfff_64zU4_Cs3tYFHG6bRoq7MCHOcFHuqr8HZxNFVJ6y7VwDvzjLfQPcnzt4B5XD8u916sJjXzbZQ9PeKyl-OqPEtctPHlvSwNYZdsmOqPXJ94m_P98iud-SGvvBo0y9vk29gKLQribucLWht4fMKp2XRM0QWn9M3M3mFZTMNlVVJx9hYJfHpFVa_AxfFf3PpEdbA07bfcGkc6XGv2pWezpovdNxO-LlDpuO3n49PAj-NIdBZHq-CMpGhMpFRuco56JCpSMVG8BKCKKVKCbFfavJQgapdGmQibWNTCq00Z0qb5C4ZVCDnfUJ1aKO8xBkfmjHNlZKcy0za2AqjUlEOSbJRQaE9VDlOzJgX7v6NQ8rSSrRAxRVecUMSdFyLFqrjH_RHqN2OFoG23YN6eVF4vy0gAQkNhrFJrJhBaByBkGaWZ1ymisOrPkbbKNqu1W67KA4h0M15CoIakqeOAsE2KqzmuZDrpinefTz7D6JPpz2i557I1iAOLX0HBfwmBPHqUR70KGHL0L3lfbTkjVSaInJ5eZ4kDDg31r19-Um3jF-KFXqVqdctTSoEJABDcq91hk6yMaL-QZw8JLznJj3R91eq2aXDOof4kvEwv__313pAbkAgy1ztHzsgg9VybR5CsLhSj5z__wSonmsh priority: 102 providerName: Scholars Portal |
| Title | The Relationship of Retinal Vessel Diameters and Fractal Dimensions with Blood Pressure and Cardiovascular Risk Factors |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/25188273 https://www.proquest.com/docview/1560109334 https://www.proquest.com/docview/1560588540 https://pubmed.ncbi.nlm.nih.gov/PMC4154709 https://doaj.org/article/8820e065032b4e268487905f767a5b7d http://dx.doi.org/10.1371/journal.pone.0106551 |
| Volume | 9 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3db9MwELegkxAvExsfK4xiEBLwkC0fTuw8obWsDKQONNjUt8h2nK2iS0rTin-fO8cNBE3Ai6XE5yi58zl39t3vCHkpwkiKqCi8nBexx3QaeSJXzItFYRIm_URwTE6enCYn5-zjNJ66DbfahVVu1kS7UOeVxj3yw8C6DuB-s7eL7x5WjcLTVVdC4zbZQugyDOni09bhAl1OEpcuF_Hg0EnnYFGV5gB9oTgOOr8ji9rfrs29xbyqbzI8_4yf_O2HNL5Htp0lSY8a0e-QW6bcJXcm7qx8l-w4ta3pa4ct_eY--QHTgrYBcFezBa0KuF5hbSx6gTjic_puJq8xSKamsszpGNOoJN69xlh3GEVx75YOMeKdNtmFS2NJR53YVno2q7_RcVPP5wE5Hx9_HZ14rvaCp5M0XHl5JH1lAqNSlXKQGFOBCo3gOZhMSuUSLL3YpL4CwVqnxwS6CE0utNKcKW2ih6RXAp_3CNV-EaQ5VvTQjGmulORcJrIIC2FULPI-iTYiyLQDJsf6GPPMnrZxcFAajmYouMwJrk-8dtSiAeb4B_0QpdvSIqy2vVEtLzOnpRm4G75BozUKFTMIhCMQwKzgCZex4vCqz3BuZE2Oars4ZEdg1qY8Bkb1yQtLgdAaJcbuXMp1XWcfPl38B9GXsw7RK0dUVMAOLV2-BHwTQnZ1KPc7lLBA6E73Hs7kDVfq7JcqwcjN7L65-3nbjQ_FeLzSVOuGJhYCzP0-edQoQ8vZEDH-wCruE95Rkw7ruz3l7Moim4M1ybifPv77az0hd8FsZTbSj-2T3mq5Nk_BNFypgdV_aMUowHb8fkC2hsenn88GdrMF2gkTPwHiiWpq |
| linkProvider | ProQuest |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3db9MwELdGkYAXxMbHCoMZBAIesuXDiZ0HhPZBtbJ1SGOb-hZsx9kquqQ0rSb-Kf5G7hI3EDQBL3tsfI7cu_P5d_F9EPJS-IEUQZY5Kc9Ch-k4cESqmBOKzERMupHgmJw8OIz2TtjHYThcIj8WuTAYVrmwiZWhTguN38g3vcp1APebvZ98c7BrFN6uLlpo1Gqxb75fgstWvuvvgnxf-X7vw_HOnmO7Cjg6iv2ZkwbSVcYzKlYxh7Uw5SnfCJ4CGFAqlYBhQhO7CpZcwXnj6cw3qdBKc6a0CeC9N8hNOHhd3FF82Dh4YDuiyKbnBdzbtNqwMSlys4G-Vxh6reOv6hLQnAWdybgorwK6f8Zr_nYA9u6Ruxa50q1a1ZbJkslXyK2BvZtfIcvWTJT0ja1l_fY-uQQ1pE3A3floQosMfs-wFxc9xbrlY7o7khcYlFNSmae0h2lbEp9eYGw9zKL4rZhuY4Q9rbMZp6Yi3WnF0tKjUfmV9ur-QQ_IybVI5SHp5MDnVUK1m3lxih1ENGOaKyU5l5HM_EwYFYq0S4KFCBJtC6FjP45xUt3ucXCIao4mKLjECq5LnGbWpC4E8g_6bZRuQ4tlvKsHxfQssVYhAffGNQiSA18xg4V3BBZMy3jEZag4LHUddSOpc2IbY5RsAYyOeQiM6pIXFQWW8sgxVuhMzssy6X86_Q-iz0ctoteWKCuAHVra_Az4T1girEW51qIEg6Rbw6uoyQuulMmvrQszF9p99fDzZhhfivF_uSnmNU0oBLgXXfKo3gwNZ32sKQgovEt4a5u0WN8eyUfnVSV1QK-Mu_Hjvy9rndzeOx4cJAf9w_0n5A5AZlZFGbI10plN5-YpwNKZelbZAkq-XLfx-QlGraQb |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3db9MwELdGkSZeEBsfKwxmEAh4yJoPJ04eENpWqo2xgcY29S3Yjr1VdElpWk38a_x13CVuIGgCXvbY-By5d-fz7-L7IOR57AciDoxxMm5Ch6kkcOJMMieMjY6YcKOYY3LywWG0e8LeD8PhEvmxyIXBsMqFTawMdVYo_Ebe8yrXAdxv1jM2LOJTf_B28s3BDlJ407pop1GryL7-fgnuW_lmrw-yfuH7g3fHO7uO7TDgqCjxZ04WCFdqT8tEJhzWxaQnfR3zDICBlJkAPBPqxJWw_Araa08ZX2exkoozqXQA771BbvIg9HCP8WHj7IEdiSKbqhdwr2c1Y3NS5HoT_bAw9FpHYdUxoDkXOpNxUV4Fev-M3fztMBzcIbctiqVbtdqtkCWdr5LlA3tPv0pWrMko6Stb1_r1XXIJKkmb4Lvz0YQWBn7PsC8XPcUa5mPaH4kLDNApqcgzOsAULoFPLzDOHmZR_G5MtzHantaZjVNdke604mrp0aj8Sgd1L6F75ORapHKfdHLg8xqhyjVekmE3EcWY4lIKzkUkjG9iLcM465JgIYJU2aLo2JtjnFY3fRyco5qjKQoutYLrEqeZNamLgvyDfhul29BiSe_qQTE9S62FSMHVcTUC5sCXTGMRnhiLpxkecRFKDkvdQN1I6_zYxjClWwCpEx4Co7rkWUWBZT1y3CBnYl6W6d7H0_8g-nzUInppiUwB7FDC5mrAf8JyYS3K9RYlGCfVGl5DTV5wpUx_bWOYudDuq4efNsP4UowFzHUxr2nCOAZXo0se1Juh4ayP9QUBkXcJb22TFuvbI_novKqqDkiWcTd5-PdlbZBlMDvph73D_UfkFqBnVgUcsnXSmU3n-jEg1Jl8UpkCSr5ct-35CddBqFE |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+Relationship+of+Retinal+Vessel+Diameters+and+Fractal+Dimensions+with+Blood+Pressure+and+Cardiovascular+Risk+Factors&rft.jtitle=PloS+one&rft.au=Zhu%2C+Pengli&rft.au=Huang%2C+Feng&rft.au=Lin%2C+Fan&rft.au=Li%2C+Qiaowei&rft.date=2014-09-04&rft.pub=Public+Library+of+Science&rft.eissn=1932-6203&rft.volume=9&rft.issue=9&rft.spage=e106551&rft_id=info:doi/10.1371%2Fjournal.pone.0106551&rft.externalDBID=HAS_PDF_LINK&rft.externalDocID=3423268031 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1932-6203&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1932-6203&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1932-6203&client=summon |