Obesity and Hepatic Steatosis Are Associated with Elevated Serum Amyloid Beta in Metabolically Stressed APPswe/PS1dE9 Mice - Shie, Feng-Shiun; Shiao, Young-Ji; Yeh, Chih-Wen; Lin, Chien-Hung; Tzeng, Tsai-Teng; Hsu, Hao-Chieh; Huang, Fong-Lee; Tsay, Huey-Jen; Liu, Hui-Kang (PloS one, 2015)
Keywords: Alzheimer's disease; Amyloid beta-Peptides - blood; Amyloid beta-Protein Precursor - genetics; Amyloid beta-Protein Precursor - metabolism; Analysis; Analysis of Variance; Animals; Blood Glucose - metabolism; Body weight; Body weight gain; Brain research; Care and treatment; Correlation analysis; Data processing; Diabetes Mellitus, Experimental - blood; Diabetes Mellitus, Experimental - genetics; Diabetes Mellitus, Experimental - metabolism; Disease Models, Animal; Fatty Acids, Nonesterified - blood; Fatty liver; Fatty Liver - blood; Genetic engineering; Glucose; Glycoproteins; High fat diet; Humans; Hyperglycemia; Insulin resistance; Leptin - blood; Lipids - blood; Liver; Liver - metabolism; Liver - pathology; Male; Metabolism; Mice; Mice, Inbred C57BL; Mice, Transgenic; Obesity; Obesity - blood; Peptide Fragments - blood; Presenilin-1 - genetics; Presenilin-1 - metabolism; Risk factors; Rodents; Steatosis; Streptozocin; Stress, Physiological - genetics; Stresses; Transgenic mice; Triglycerides; Triglycerides - metabolism; Variance analysis; Weight Gain; β-Amyloid; United States--US; Taiwan