The Prescription Pattern of Chinese Herbal Products That Contain Dang-Qui and Risk of Endometrial Cancer among Tamoxifen-Treated Female Breast Cancer Survivors in Taiwan: A Population-Based Study

• Published in: PloS one Vol. 9; no. 12; p. e113887
• Main Authors: Wu, Chien-Tung, Lai, Jung-Nien, Tsai, Yueh-Ting
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 08.12.2014; Public Library of Science (PLoS)
• Subjects: Adult; Aged; Antineoplastic Agents, Hormonal - adverse effects; Breast cancer; Breast Neoplasms - drug therapy; Cancer; Cancer research; Cancer survivors; Care and treatment; Drugs, Chinese Herbal - adverse effects; Endometrial cancer; Endometrial Neoplasms - epidemiology; Endometrial Neoplasms - etiology; Endometrium; Female; Health hazards; Health risks; Herb-Drug Interactions; Herbal medicine; Humans; Invasiveness; Medical diagnosis; Medicine and Health Sciences; Medicine, Chinese Traditional; Middle Aged; National health insurance; Neoplasms, Second Primary; Odds Ratio; Online databases; Population studies; Population Surveillance; Population-based studies; Practice Patterns, Physicians; Regression analysis; Risk; Risk Factors; Risk reduction; Taiwan; Tamoxifen; Tamoxifen - adverse effects; Traditional Chinese medicine; Uterine cancer; Young Adult; Taiwan

The increased practice of traditional Chinese medicine worldwide has raised concerns regarding herb-drug interactions. We analyzed the usage of Chinese herbal products containing dang-qui and investigated whether dang-qui therapy increases endometrial cancer risk among tamoxifen-treated breast cance...