Optimization of SPECT-CT Hybrid Imaging Using Iterative Image Reconstruction for Low-Dose CT: A Phantom Study

• Published in: PloS one Vol. 10; no. 9; p. e0138658
• Main Authors: Grosser, Oliver S., Kupitz, Dennis, Ruf, Juri, Czuczwara, Damian, Steffen, Ingo G., Furth, Christian, Thormann, Markus, Loewenthal, David, Ricke, Jens, Amthauer, Holger
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 21.09.2015; Public Library of Science (PLoS)
• Subjects: Abdomen; Adult; Algorithms; Attenuation; CAT scans; Computation; Computed tomography; Diagnostic software; Diagnostic systems; Drug dosages; Emissions; Exposure; Humans; Image Enhancement - methods; Image processing; Image Processing, Computer-Assisted - methods; Image quality; Image reconstruction; Iterative methods; Laboratories; Medical diagnosis; Medical imaging; Methods; Multimodal Imaging - instrumentation; Multimodal Imaging - methods; Noise; Nuclear medicine; Optimization; Pediatrics; Phantoms, Imaging; Photon emission; Positron emission; Positron emission tomography; Quality; Radiation; Radiation Dosage; Radiation effects; Radiology; Reproducibility of Results; Single photon emission computed tomography; Tomography; Tomography, Emission-Computed, Single-Photon - instrumentation; Tomography, Emission-Computed, Single-Photon - methods; Tomography, X-Ray Computed - instrumentation; Tomography, X-Ray Computed - methods; X ray tubes; X-Rays; Germany; United States > US

Hybrid imaging combines nuclear medicine imaging such as single photon emission computed tomography (SPECT) or positron emission tomography (PET) with computed tomography (CT). Through this hybrid design, scanned patients accumulate radiation exposure from both applications. Imaging modalities have...