The prevalence of esophageal cancer after caustic and pesticide ingestion: A nationwide cohort study

• Published in: PloS one Vol. 15; no. 12; p. e0243922
• Main Authors: Mu, Han-Wei, Chen, Chun-Hung, Yang, Kai-Wei, Pan, Chi-Syuan, Lin, Cheng-Li, Hung, Dong-Zong
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 29.12.2020; Public Library of Science (PLoS)
• Subjects: Adult; Age; Aged; Alcohol; Biology and Life Sciences; Cancer; Carcinogenesis; Carcinogens; Carcinoma - chemically induced; Carcinoma - epidemiology; Carcinoma - pathology; Cardiovascular disease; Causes of; Caustics - poisoning; Cerebrovascular disease; Chronic obstructive pulmonary disease; Codes; Cohort analysis; Cohort Studies; Comorbidity; Complications and side effects; Confidence intervals; Corrosion prevention; Detergents - poisoning; Detergents, Synthetic; Diabetes; Drinking behavior; Eating - drug effects; Emergency medical care; Esophageal cancer; Esophageal carcinoma; Esophageal Neoplasms - chemically induced; Esophageal Neoplasms - epidemiology; Esophageal Neoplasms - pathology; Esophagus; Female; Health aspects; Health insurance; Health risks; Hospitals; Humans; Hypertension; Illnesses; Ingestion; Insurance; Intoxication; Male; Medicine; Medicine and Health Sciences; Middle Aged; Pesticides; Pesticides - poisoning; Physical Sciences; Poisoning; Proportional Hazards Models; Risk analysis; Risk Factors; Statistics; Surfactants; Toxicology; Taiwan; China

Habits such as smoking and alcohol drinking and existing esophageal malfunction are considered the main risk factors for esophageal carcinogenesis. Caustic ingestion of acidic or alkaline agents or strong irritants can induce severe esophageal corrosive injury and increase esophageal cancer risk. We...