Expression of the AcrAB Components of the AcrAB-TolC Multidrug Efflux Pump of Yersinia enterocolitica Is Subject to Dual Regulation by OmpR

• Published in: PloS one Vol. 10; no. 4; p. e0124248
• Main Authors: Raczkowska, Adrianna, Trzos, Joanna, Lewandowska, Olga, Nieckarz, Marta, Brzostek, Katarzyna
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 20.04.2015; Public Library of Science (PLoS)
• Subjects: Antibiotics; Bacteria; Bacterial Proteins - metabolism; Base Sequence; beta-Galactosidase - metabolism; Bile salts; Binding Sites; Biofilms; Biology; Cell division; Deoxyribonucleic acid; DNA; Drug resistance; E coli; Ecological niches; Efflux; Electrophoresis, Polyacrylamide Gel; Electrophoretic mobility; Escherichia coli; Galactosidase; Gel electrophoresis; Gene expression; Gene Expression Regulation, Bacterial; Genes; Genes, MDR; Genes, Reporter; Genetic analysis; Genomes; Gram-negative bacteria; Green Fluorescent Proteins - metabolism; Kinases; Laboratories; Lac Operon; Mass spectrometry; Mass spectroscopy; Membrane proteins; Membrane Proteins - biosynthesis; Molecular Sequence Data; Niches; Operons; Organic chemistry; Plasmids - metabolism; Promoter Regions, Genetic; Promoters; Proteins; Reporter gene; RNA - metabolism; Salmonella; Salmonella enterica; Salts; Signal transduction; Sodium lauryl sulfate; Temperature; Trans-Activators - metabolism; Transcription; Yersinia enterocolitica; Yersinia enterocolitica - metabolism; Yttrium; β-Galactosidase; Poland

OmpR is a transcriptional regulator implicated in the control of various cellular processes and functions in Enterobacteriaceae. This study was undertaken to identify genes comprising the OmpR regulon in the human gastrointestinal pathogen Yersinia enterocolitica. Derivatives of an ompR-negative str...