Real-world clinical predictors of manic/hypomanic episodes among outpatients with bipolar disorder

• Published in: PloS one Vol. 16; no. 12; p. e0262129
• Main Authors: Tokumitsu, Keita, Norio, Yasui-Furukori, Adachi, Naoto, Kubota, Yukihisa, Watanabe, Yoichiro, Miki, Kazuhira, Azekawa, Takaharu, Edagawa, Koji, Katsumoto, Eiichi, Hongo, Seiji, Goto, Eiichiro, Ueda, Hitoshi, Kato, Masaki, Nakagawa, Atsuo, Kikuchi, Toshiaki, Tsuboi, Takashi, Watanabe, Koichiro, Shimoda, Kazutaka, Yoshimura, Reiji
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 31.12.2021; Public Library of Science (PLoS)
• Subjects: Adolescent; Adult; Affect; Age Factors; Aged; Aged, 80 and over; Antidepressants; Antidepressive Agents - therapeutic use; Bipolar disorder; Bipolar Disorder - complications; Bipolar Disorder - physiopathology; Body Mass Index; Care and treatment; Chi-square test; Clinical medicine; Comorbidity; Complications and side effects; Cycles; Diagnosis; Drug abuse; Drug therapy; Female; Health risks; Health services; Health Status Indicators; Humans; Japan - epidemiology; Male; Mania - physiopathology; Medicine; Medicine and Health Sciences; Mental disorders; Middle Aged; Mood; Observational studies; Outpatients; Patients; Personality; Personality disorders; Personality Disorders - complications; Physical Sciences; Polls & surveys; Prevalence; Psychiatry; Psychotropic drugs; Questionnaires; Regression analysis; Research and Analysis Methods; Retrospective Studies; Risk; Risk analysis; Risk factors; Society; Substance use disorder; Substance-Related Disorders - complications; Suicides & suicide attempts; Surveys and Questionnaires; Treatment Outcome; Young Adult; Japan

Bipolar disorder is a mental illness in which manic and depressive states are repeated, causing psychosocial dysfunction. Manic/hypomanic episodes cause problems with interpersonal, social and financial activities, but there is limited evidence regarding the predictors of manic/hypomanic episodes in...