AMPA Receptor Antagonist NBQX Decreased Seizures by Normalization of Perineuronal Nets - Chen, Wen; Li, Yan-Shuang; Gao, Jing; Lin, Xiao-Ying; Li, Xiao-Hong (PloS one, 2016)
Keywords: Aggrecan; Aggrecans - metabolism; AMPA receptors; Analysis; Animals; Anticonvulsants - pharmacology; Anticonvulsants - therapeutic use; Behavior, Animal - drug effects; Behavioral plasticity; Biology and Life Sciences; Brain; Care and treatment; Chondroitin ABC lyase; Chondroitin ABC Lyase - pharmacology; Chondroitin sulfate; Degradation; Developmental plasticity; Disease Models, Animal; Down-Regulation - drug effects; Epilepsy; Epilepsy - chemically induced; Epilepsy - pathology; Epilepsy - prevention & control; Experiments; Extracellular matrix; Health aspects; Immunohistochemistry; Interneurons; Laboratory animals; Latency; Male; Medicine and Health Sciences; Nervous system; Nets; Neurocan; Neurocan - metabolism; Neurology; Neurons; Parvalbumin; Pentylenetetrazole; Pentylenetetrazole - toxicity; Perineuronal nets; Peripheral Nerves - drug effects; Peripheral Nerves - metabolism; Prefrontal cortex; Prefrontal Cortex - metabolism; Quinoxalines - pharmacology; Quinoxalines - therapeutic use; Rats; Rats, Wistar; Receptors, AMPA - antagonists & inhibitors; Receptors, AMPA - metabolism; Research and Analysis Methods; Rodents; Seizing; Seizures; Seizures (Medicine); Synaptic plasticity; Synaptogenesis; Tenascin; Tenascin - metabolism; Tenascin R; α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors; China