Sustained Release of BMP-2 in Bioprinted Alginate for Osteogenicity in Mice and Rats - Poldervaart, Michelle T.; Wang, Huanan; van der Stok, Johan; Weinans, Harrie; Leeuwenburgh, Sander C. G.; Öner, F. Cumhur; Dhert, Wouter J. A.; Alblas, Jacqueline (PloS one, 2013)
Keywords: 3D printing; Alginates - pharmacology; Alginic acid; Animals; Biocompatibility; Biodegradation; Biological activity; Biological properties; Biology; Biomechanics; Biomedical materials; Bioprinting - methods; Bone growth; Bone morphogenetic protein 2; Bone Morphogenetic Protein 2 - metabolism; Bone morphogenetic proteins; Calcium; Calcium phosphate; Calcium phosphates; Cell Differentiation - drug effects; Comparative analysis; Controlled release; Delayed-Action Preparations; Differentiation; Drug dosages; Engineering; Female; Fractures; Gelatin; Gelatin - pharmacology; Glucuronic Acid - pharmacology; Goats; Growth factors; Hexuronic Acids - pharmacology; Humans; Hydrogels; Hydroxyapatites - pharmacology; Implantation; Kinetics; Materials Science; Medicine; Mice, Nude; Microparticles; Microspheres; Multipotent Stem Cells - cytology; Multipotent Stem Cells - drug effects; Multipotent Stem Cells - metabolism; Osteocalcin - metabolism; Osteogenesis; Osteogenesis - drug effects; Phosphates; Polymers; Printing; Product introduction; Proteins; Rats; Rats, Wistar; Scaffolds; Stromal cells; Stromal Cells - cytology; Stromal Cells - drug effects; Stromal Cells - metabolism; Subcutaneous Tissue - metabolism; Surgical implants; Sustained release; Three dimensional printing; Tissue engineering; Tissue Scaffolds - chemistry; Vehicles; Netherlands